Supramolecular synthons provide the most important and successful approach to the rational design of co-crystals. Yet, the relatively low success rate of co-crystal screening experiments demonstrates that the availability of appropriate synthons is only one of many factors that influence co-crystallisation. The aim of our work was to identify other factors and to use them in developing design strategies that are complementary to supramolecular synthons.
|Name||RSC Drug Discovery Series|
|Publisher||Royal Society of Chemistry|