Short-term effects of ambient particles on cardiovascular and respiratory mortality

Antonis Analitis, Klea Katsouyanni, Konstantina Dimakopoulou, Evangelia Samoli, Aristidis K Nikoloulopoulos, Yannis Petasakis, Giota Touloumi, Joel Schwartz, Hugh Anderson, Koldo Cambra, Francesco Forastiere, Denis Zmirou, Judith Vonk, Luke Clancy, Bohumir Kriz, Janos Bobvos, Juha Pekkanen

Research output: Contribution to journalArticlepeer-review

276 Citations (Scopus)


Background: Particulate air pollution is associated with increased mortality. There is a need for European results from multicountry databases concerning cause-specific mortality to obtain more accurate effect estimates. Methods: We report the estimated effects of ambient particle concentrations (black smoke and particulate matter less than 10 [mu]m [PM10]) on cardiovascular and respiratory mortality, from 29 European cities, within the Air Pollution and Health: a European Approach (APHEA2) project. We applied a 2-stage hierarchical modeling approach assessing city-specific effects first and then overall effects. City characteristics were considered as potential effect modifiers. Results: An increase in PM10 by 10 [mu]g/m3 (lag 0 + 1) was associated with increases of 0.76% (95% confidence interval = 0.47 to 1.05%) in cardiovascular deaths and 0.58% (0.21 to 0.95%) in respiratory deaths. The same increase in black smoke was associated with increases of 0.62% (0.35 to 0.90%) and 0.84% (0.11 to 1.57%), respectively. Conclusions: These effect estimates are appropriate for health impact assessment and standard-setting procedures.
Original languageEnglish
Pages (from-to)230-233
Number of pages4
Issue number2
Publication statusPublished - Mar 2006

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