Silver cations fold i-motif at neutral pH

Henry A. Day, Camille Huguin, Zoe A. E. Waller

Research output: Contribution to journalArticlepeer-review

130 Citations (Scopus)


i-Motif DNA structures have previously been utilised for many different nanotechnological applications, but all have used acidic conditions to fold the DNA. Herein we describe the use of silver cations to fold an i-motif forming DNA sequence at physiological pH. Subsequent DNA unfolding can be achieved by chelation with cysteine.
Original languageEnglish
Pages (from-to)7696-7698
Number of pages3
JournalChemical Communications
Issue number70
Publication statusPublished - 1 Jan 2013

Cite this