Silver cations fold i-motif at neutral pH

Henry A. Day; Camille Huguin; Zoe A. E. Waller

doi:10.1039/c3cc43495h

Silver cations fold i-motif at neutral pH

Henry A. Day, Camille Huguin, Zoe A. E. Waller

Research output: Contribution to journal › Article › peer-review

118 Citations (Scopus)

Abstract

i-Motif DNA structures have previously been utilised for many different nanotechnological applications, but all have used acidic conditions to fold the DNA. Herein we describe the use of silver cations to fold an i-motif forming DNA sequence at physiological pH. Subsequent DNA unfolding can be achieved by chelation with cysteine.

Original language	English
Pages (from-to)	7696-7698
Number of pages	3
Journal	Chemical Communications
Volume	49
Issue number	70
DOIs	https://doi.org/10.1039/c3cc43495h
Publication status	Published - 1 Jan 2013

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10.1039/c3cc43495h

Cite this

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abstract = "i-Motif DNA structures have previously been utilised for many different nanotechnological applications, but all have used acidic conditions to fold the DNA. Herein we describe the use of silver cations to fold an i-motif forming DNA sequence at physiological pH. Subsequent DNA unfolding can be achieved by chelation with cysteine.",

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AB - i-Motif DNA structures have previously been utilised for many different nanotechnological applications, but all have used acidic conditions to fold the DNA. Herein we describe the use of silver cations to fold an i-motif forming DNA sequence at physiological pH. Subsequent DNA unfolding can be achieved by chelation with cysteine.

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