Slowly resolving global myocardial inflammation/oedema in Tako-Tsubo cardiomyopathy: Evidence from T2-weighted cardiac MRI

Christopher Neil; Thanh Ha Nguyen; Angela Kucia; Benjamin Crouch; Aaron Sverdlov; Yuliy Chirkov; Gnanadevan Mahadavan; Joseph Selvanayagam; Dana Dawson; John Beltrame; Christopher Zeitz; Steven Unger; Thomas Redpath; Michael Frenneaux; John Horowitz

doi:10.1136/heartjnl-2011-301481

Slowly resolving global myocardial inflammation/oedema in Tako-Tsubo cardiomyopathy: Evidence from T2-weighted cardiac MRI

Christopher Neil, Thanh Ha Nguyen, Angela Kucia, Benjamin Crouch, Aaron Sverdlov, Yuliy Chirkov, Gnanadevan Mahadavan, Joseph Selvanayagam, Dana Dawson, John Beltrame, Christopher Zeitz, Steven Unger, Thomas Redpath, Michael Frenneaux, John Horowitz

Research output: Contribution to journal › Article › peer-review

106 Citations (Scopus)

Abstract

Tako-Tsubo cardiomyopathy (TTC) is associated with regional left ventricular dysfunction, independent of the presence of fixed coronary artery disease. Previous studies have used T2-weighted cardiac MRI to demonstrate the presence of periapical oedema. The authors sought to determine the distribution, resolution and correlates of oedema in TTC.

Original language	English
Pages (from-to)	1278-1284
Number of pages	7
Journal	Heart
Volume	98
Issue number	17
Early online date	11 Jul 2012
DOIs	https://doi.org/10.1136/heartjnl-2011-301481
Publication status	Published - Sept 2012

Keywords

Adult
Aged
Aged, 80 and over
C-Reactive Protein
Case-Control Studies
Edema
Female
Humans
Inflammation
Magnetic Resonance Imaging, Cine
Male
Middle Aged
Myocardium
Natriuretic Peptide, Brain
Normetanephrine
Peptide Fragments
Takotsubo Cardiomyopathy

Access to Document

10.1136/heartjnl-2011-301481

Cite this

Neil, C., Nguyen, T. H., Kucia, A., Crouch, B., Sverdlov, A., Chirkov, Y., Mahadavan, G., Selvanayagam, J., Dawson, D., Beltrame, J., Zeitz, C., Unger, S., Redpath, T., Frenneaux, M., & Horowitz, J. (2012). Slowly resolving global myocardial inflammation/oedema in Tako-Tsubo cardiomyopathy: Evidence from T2-weighted cardiac MRI. Heart, 98(17), 1278-1284. https://doi.org/10.1136/heartjnl-2011-301481

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title = "Slowly resolving global myocardial inflammation/oedema in Tako-Tsubo cardiomyopathy: Evidence from T2-weighted cardiac MRI",

abstract = "Tako-Tsubo cardiomyopathy (TTC) is associated with regional left ventricular dysfunction, independent of the presence of fixed coronary artery disease. Previous studies have used T2-weighted cardiac MRI to demonstrate the presence of periapical oedema. The authors sought to determine the distribution, resolution and correlates of oedema in TTC.",

keywords = "Adult, Aged, Aged, 80 and over, C-Reactive Protein, Case-Control Studies, Edema, Female, Humans, Inflammation, Magnetic Resonance Imaging, Cine, Male, Middle Aged, Myocardium, Natriuretic Peptide, Brain, Normetanephrine, Peptide Fragments, Takotsubo Cardiomyopathy",

author = "Christopher Neil and Nguyen, {Thanh Ha} and Angela Kucia and Benjamin Crouch and Aaron Sverdlov and Yuliy Chirkov and Gnanadevan Mahadavan and Joseph Selvanayagam and Dana Dawson and John Beltrame and Christopher Zeitz and Steven Unger and Thomas Redpath and Michael Frenneaux and John Horowitz",

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doi = "10.1136/heartjnl-2011-301481",

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Neil, C, Nguyen, TH, Kucia, A, Crouch, B, Sverdlov, A, Chirkov, Y, Mahadavan, G, Selvanayagam, J, Dawson, D, Beltrame, J, Zeitz, C, Unger, S, Redpath, T, Frenneaux, M & Horowitz, J 2012, 'Slowly resolving global myocardial inflammation/oedema in Tako-Tsubo cardiomyopathy: Evidence from T2-weighted cardiac MRI', Heart, vol. 98, no. 17, pp. 1278-1284. https://doi.org/10.1136/heartjnl-2011-301481

TY - JOUR

T1 - Slowly resolving global myocardial inflammation/oedema in Tako-Tsubo cardiomyopathy: Evidence from T2-weighted cardiac MRI

AU - Neil, Christopher

AU - Nguyen, Thanh Ha

AU - Kucia, Angela

AU - Crouch, Benjamin

AU - Sverdlov, Aaron

AU - Chirkov, Yuliy

AU - Mahadavan, Gnanadevan

AU - Selvanayagam, Joseph

AU - Dawson, Dana

AU - Beltrame, John

AU - Zeitz, Christopher

AU - Unger, Steven

AU - Redpath, Thomas

AU - Frenneaux, Michael

AU - Horowitz, John

PY - 2012/9

Y1 - 2012/9

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AB - Tako-Tsubo cardiomyopathy (TTC) is associated with regional left ventricular dysfunction, independent of the presence of fixed coronary artery disease. Previous studies have used T2-weighted cardiac MRI to demonstrate the presence of periapical oedema. The authors sought to determine the distribution, resolution and correlates of oedema in TTC.

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - C-Reactive Protein

KW - Case-Control Studies

KW - Edema

KW - Female

KW - Humans

KW - Inflammation

KW - Magnetic Resonance Imaging, Cine

KW - Male

KW - Middle Aged

KW - Myocardium

KW - Natriuretic Peptide, Brain

KW - Normetanephrine

KW - Peptide Fragments

KW - Takotsubo Cardiomyopathy

U2 - 10.1136/heartjnl-2011-301481

DO - 10.1136/heartjnl-2011-301481

M3 - Article

C2 - 22791656

SN - 1355-6037

VL - 98

SP - 1278

EP - 1284

JO - Heart

JF - Heart

IS - 17

ER -