Small RNA analysis in Sindbis virus infected human HEK293 cells

Andras Donaszi-Ivanov; Irina Mohorianu; Tamas Dalmay; Penny P Powell

doi:10.1371/journal.pone.0084070

Small RNA analysis in Sindbis virus infected human HEK293 cells

Andras Donaszi-Ivanov, Irina Mohorianu, Tamas Dalmay, Penny P Powell

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Abstract

In contrast to the defence mechanism of RNA interference (RNAi) in plants and invertebrates, its role in the innate response to virus infection of mammals is a matter of debate. Since RNAi has a well-established role in controlling infection of the alphavirus Sindbis virus (SINV) in insects, we have used this virus to investigate the role of RNAi in SINV infection of human cells.

Original language	English
Article number	e84070
Journal	PLoS One
Volume	8
Issue number	12
DOIs	https://doi.org/10.1371/journal.pone.0084070
Publication status	Published - 31 Dec 2013

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Donaszi-Ivanov_etal_2013_PLoSONEFinal published version, 1.27 MB

Pestivirus Evasion of the Intracellular Antiviral Response to Infection (Transfer of BBSRC Awardl)
Powell, P.
Biotechnology and Biological Sciences Research Council
1/07/07 → 31/08/09
Project: Research

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Small RNA analysis in Sindbis virus infected human HEK293 cells

Abstract

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Projects

Pestivirus Evasion of the Intracellular Antiviral Response to Infection (Transfer of BBSRC Awardl)

Cite this