Sodium glucose co-transporter 2 (SGLT2) inhibitors in heart failure with preserved ejection fraction: A systematic review and meta-analysis

Vasiliki Tsampasian, Hussein Elghazaly, Rahul Kumar Chattopadhyay, Omar Ali, Natasha Corballis, Panagiota Anna Chousou, Allan Clark, Pankaj Garg, Vassilios Vassiliou

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)
10 Downloads (Pure)


Whilst heart failure with preserved ejection fraction (HFpEF) is increasingly studied, the search for a single pharmacotherapeutic agent that will improve hard endpoints like hospitalization and mortality still continues.1 Given the various subphenotypes of HFpEF,2 this makes it difficult for a single agent to be universally beneficial. The recent publication of EMPEROR-PRESEVED3 was an instrumental time for an updated meta-analysis focused on sodium glucose co-transporter 2 inhibitors (SGLT2i) use in HFpEF.
Original languageEnglish
Pages (from-to)e227–e229
Number of pages3
JournalEuropean Journal of Preventive Cardiology
Issue number6
Early online date1 Dec 2021
Publication statusPublished - Apr 2022

Cite this