Sphingosine kinase-1 (SphK1) was shown in preclinical models and non-genitourinary cancers to be instrumental in cancer progression, adaptation to hypoxia and in tumour angiogenesis. No data were available in human prostate cancer. The present study was designed to assess SphK1 expression and activity in radical prostatectomy specimens and to research correlations with clinical features.
- Microarray Analysis
- Middle Aged
- Neoplasm Proteins
- Phosphotransferases (Alcohol Group Acceptor)
- Prostatic Neoplasms