Statin use is associated with reduced risk of histologic subtypes of esophageal cancer: A nested case-control analysis

Research output: Contribution to journalArticle

37 Citations (Scopus)
7 Downloads (Pure)

Abstract

Most patients with esophageal adenocarcinoma (EAC) or squamous cell cancer (ESCC) present with advanced, incurable disease. Statins have reported anti-carcinogenic effects and may be chemoprotective. We investigated the association between regular use of statins and the main histologic subtypes of esophageal malignancy (EAC, esophagogastric junctional adenocarcinoma [EGJA], and ESCC) in the UK general population.
Original languageEnglish
Pages (from-to)661–668
Number of pages8
JournalGastroenterology
Volume146
Issue number3
Early online date5 Dec 2013
DOIs
Publication statusPublished - Mar 2014

Keywords

  • esophageal cancer
  • statins
  • aetiology

Cite this