Stereoselective synthesis of N-alkylaziridines from N-chloroamines

Sean P. Bew, David L. Hughes, Nicholas J. Palmer, Vladimir Savic, Katy M. Soapi, Martin A. Wilson

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Abstract

We report the first racemic and stereoselective synthesis of cis- and trans-N-alkylaziridines via N-chloroamines; using this methodology an N-3,4,5-trimethoxybenzylaziridine was synthesised and efficiently cleaved, affording the corresponding NH aziridine in high yield. © The Royal Society of Chemistry 2006.
Original languageEnglish
Pages (from-to)4338-4340
Number of pages3
JournalChemical Communications
Issue number41
DOIs
Publication statusPublished - 1 Jan 2006

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