Strategy for prevention of cancers of the esophagus

Junichi Akiyama, Leo Alexandre, Anushka Baruah, Navtej Buttar, Raghav Chandra, Allan B Clark, Andrew R Hart, Ernest Hawk, Daniela Kandioler, Sonja Kappel, Sheila K Krishnadath, Anamay Sharma, Ishtpreet Singh, Danielle Straub, George Triadafilopoulos, Asad Umar, Brigitte Wolf

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The following, from the 12th OESO World Conference: Cancers of the Esophagus, includes commentaries on the animal reflux-inflammation models for Barrett's esophagus and esophageal adenocarcinoma; genomic/epigenomic analyses; eflornithine-based combinations; the molecular derangements that promote neoplastic transformation; the role of COX-2 inhibitors, proton pump inhibitors, and phase II trials in Barrett's adenocarcinoma; statins in chemoprevention and treatment of esophageal cancer; and biomarkers as potential targets in Barrett's adenocarcinoma.

Original languageEnglish
Pages (from-to)108-126
Number of pages19
JournalAnnals of the New York Academy of Sciences
Volume1325
Early online date29 Sep 2014
DOIs
Publication statusPublished - Sep 2014
EventThe 12th OESO World Conference: Cancers of the Esophagus - Paris, United Kingdom
Duration: 27 Aug 201330 Aug 2013

Keywords

  • animal reflux–inflammation models
  • Barrett's adenocarcinoma
  • elofrnithine
  • COXIBs
  • PPIs
  • statins
  • biomarkers
  • OESO

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