Structural and functional analogues of the active sites of the [Fe]-, [NiFe]-, and [FeFe]-hydrogenases

Cédric Tard, Christopher Pickett

Research output: Contribution to journalArticlepeer-review

1143 Citations (Scopus)


This article sets out to review the chemistry relating to the synthesis of structural and functional analogues of the three classes of hydrogenases. This chemistry has grown explosively over the last 10 or so years since the first X-ray structures of [NiFe]- and [FeFe]-hydrogenase systems were published. There are now some 400 papers covering structural and functional aspects, with the majority of these associated with the di-iron system. As much emphasized in earlier papers
Original languageEnglish
Pages (from-to)2245-2274
Number of pages30
JournalChemical Reviews
Issue number6
Publication statusPublished - 2009

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