Supine rest reduces platelet activation and aggregation

Andrew J. M. Broadley, Peter Gapper, Matthias Schmitt, Michael P. Frenneaux

Research output: Contribution to journalArticlepeer-review

37 Citations (Scopus)


Platelet activation and aggregation are central processes in acute coronary syndromes and myocardial infarction, and are stimulated by physical and mental stress. However, it is not known if and to what extent the "ordinary" stress inherent in a person's daily routine contributes to platelet activation and aggregation. We measured platelet activation and aggregation in 12 healthy non-smokers, before and after 45 min supine rest in a calm environment. This simple manouver resulted in a highly significant fall in platelet aggregation (7.9-4.4 ohms, p
Original languageEnglish
Pages (from-to)3-7
Number of pages5
Issue number1
Publication statusPublished - Feb 2003


  • Biological Markers
  • Catecholamines
  • Humans
  • P-Selectin
  • Platelet Activation
  • Platelet Aggregation
  • Rest
  • Supine Position
  • beta-Thromboglobulin
  • von Willebrand Factor

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