Supine rest reduces platelet activation and aggregation

Andrew J. M. Broadley; Peter Gapper; Matthias Schmitt; Michael P. Frenneaux

doi:10.1080/0953710021000034447

Supine rest reduces platelet activation and aggregation

Andrew J. M. Broadley, Peter Gapper, Matthias Schmitt, Michael P. Frenneaux

Research output: Contribution to journal › Article › peer-review

37 Citations (Scopus)

Abstract

Platelet activation and aggregation are central processes in acute coronary syndromes and myocardial infarction, and are stimulated by physical and mental stress. However, it is not known if and to what extent the "ordinary" stress inherent in a person's daily routine contributes to platelet activation and aggregation. We measured platelet activation and aggregation in 12 healthy non-smokers, before and after 45 min supine rest in a calm environment. This simple manouver resulted in a highly significant fall in platelet aggregation (7.9-4.4 ohms, p

Original language	English
Pages (from-to)	3-7
Number of pages	5
Journal	Platelets
Volume	14
Issue number	1
DOIs	https://doi.org/10.1080/0953710021000034447
Publication status	Published - Feb 2003

Keywords

Biological Markers
Catecholamines
Humans
P-Selectin
Platelet Activation
Platelet Aggregation
Rest
Supine Position
beta-Thromboglobulin
von Willebrand Factor

Access to Document

10.1080/0953710021000034447

Cite this

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AU - Broadley, Andrew J. M.

AU - Gapper, Peter

AU - Schmitt, Matthias

AU - Frenneaux, Michael P.

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N2 - Platelet activation and aggregation are central processes in acute coronary syndromes and myocardial infarction, and are stimulated by physical and mental stress. However, it is not known if and to what extent the "ordinary" stress inherent in a person's daily routine contributes to platelet activation and aggregation. We measured platelet activation and aggregation in 12 healthy non-smokers, before and after 45 min supine rest in a calm environment. This simple manouver resulted in a highly significant fall in platelet aggregation (7.9-4.4 ohms, p

AB - Platelet activation and aggregation are central processes in acute coronary syndromes and myocardial infarction, and are stimulated by physical and mental stress. However, it is not known if and to what extent the "ordinary" stress inherent in a person's daily routine contributes to platelet activation and aggregation. We measured platelet activation and aggregation in 12 healthy non-smokers, before and after 45 min supine rest in a calm environment. This simple manouver resulted in a highly significant fall in platelet aggregation (7.9-4.4 ohms, p

KW - Biological Markers

KW - Catecholamines

KW - Humans

KW - P-Selectin

KW - Platelet Activation

KW - Platelet Aggregation

KW - Rest

KW - Supine Position

KW - beta-Thromboglobulin

KW - von Willebrand Factor

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JO - Platelets

JF - Platelets

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