Suppression of venous signal in time-of-flight MR angiography of the lower extremities after administration of gadopentetate dimeglumine

N. M. Rofsky, D. E. Purdy, G. Johnson, D. R. DeCorato, J. P. Earls, G. Krinsky, J. C. Weinreb

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PURPOSE: To evaluate a magnetic resonance (MR) angiography time-of-flight technique that can effectively suppress venous signal after gadopentetate dimeglumine administration. MATERIALS AND METHODS: Twelve adult patients underwent MR angiography for the evaluation of peripheral vascular disease. Gradient-echo sequences were performed after the administration of 0.2 mmol/kg gadopentetate dimeglumine. Three sequences were compared: a nontriggered sequence; a gap sequence, an electrocardiographically triggered, segmented sequence with a 7-mm gap between saturation and imaging sections; and a no-gap sequence, a similar sequence as gap but with partially overlapping imaging and saturation sections. For each sequence, identical regions of interest were generated for arterial, venous, and background muscle tissue and noise. A paired Student t test was used to compare the signal-to-noise and contrast-to-noise ratios (C/Ns) among the sequences. In seven patients, the no-gap sequence was used to acquire MR angiograms of the distal lower extremities. RESULTS: The mean artery-muscle C/N was similar for the triggered sequences; both were statistically significantly greater than the ratios for the nontriggered sequence. Venous suppression was much better with the no-gap sequence. Overall, the best artery-vein C/N was also obtained with the no-gap sequence. MR angiograms with effective venous suppression could be obtained only with the no-gap sequence. CONCLUSION: Time-of-flight MR angiograms can be obtained with effective venous suppression after the administration of 0.2 mmol/kg gadopentetate dimeglumine.
Original languageEnglish
Pages (from-to)177-182
Number of pages6
Issue number1
Publication statusPublished - Jan 1997

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