Survival of C28Y homozygotes does not preclude screening for HFE mutations

Gavin Willis; Barbara A. Jennings; Jennie Z. Wimperis

doi:10.1136/bmj.327.7407.132

Survival of C28Y homozygotes does not preclude screening for HFE mutations

Gavin Willis, Barbara A. Jennings, Jennie Z. Wimperis

Research output: Contribution to journal › Comment/debate

44 Citations (Scopus)

Abstract

In their recent paper, Coppin et al [1] found surviving elderly C282Y homozygotes at a frequency similar to our previous study [2]. Their results illustrate clearly and simply that fatal disease is not an invariant outcome for untreated female C282Y homozyogotes and our previous study drew the same conclusion for male C282Y homozygotes.

Original language	English
Article number	132
Journal	BMJ-British Medical Journal
Volume	327
DOIs	https://doi.org/10.1136/bmj.327.7407.132
Publication status	Published - 22 Jul 2003

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10.1136/bmj.327.7407.132

Cite this

@article{373c367a06d540c099956ea0f44b56ae,

title = "Survival of C28Y homozygotes does not preclude screening for HFE mutations",

abstract = "In their recent paper, Coppin et al [1] found surviving elderly C282Y homozygotes at a frequency similar to our previous study [2]. Their results illustrate clearly and simply that fatal disease is not an invariant outcome for untreated female C282Y homozyogotes and our previous study drew the same conclusion for male C282Y homozygotes.",

author = "Gavin Willis and Jennings, {Barbara A.} and Wimperis, {Jennie Z.}",

year = "2003",

month = jul,

day = "22",

doi = "10.1136/bmj.327.7407.132",

language = "English",

volume = "327",

journal = "BMJ-British Medical Journal",

issn = "1759-2151",

publisher = "BMJ Publishing Group",

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TY - JOUR

T1 - Survival of C28Y homozygotes does not preclude screening for HFE mutations

AU - Willis, Gavin

AU - Jennings, Barbara A.

AU - Wimperis, Jennie Z.

PY - 2003/7/22

Y1 - 2003/7/22

N2 - In their recent paper, Coppin et al [1] found surviving elderly C282Y homozygotes at a frequency similar to our previous study [2]. Their results illustrate clearly and simply that fatal disease is not an invariant outcome for untreated female C282Y homozyogotes and our previous study drew the same conclusion for male C282Y homozygotes.

AB - In their recent paper, Coppin et al [1] found surviving elderly C282Y homozygotes at a frequency similar to our previous study [2]. Their results illustrate clearly and simply that fatal disease is not an invariant outcome for untreated female C282Y homozyogotes and our previous study drew the same conclusion for male C282Y homozygotes.

U2 - 10.1136/bmj.327.7407.132

DO - 10.1136/bmj.327.7407.132

M3 - Comment/debate

VL - 327

JO - BMJ-British Medical Journal

JF - BMJ-British Medical Journal

SN - 1759-2151

M1 - 132

ER -