TY - JOUR
T1 - Synthesis of a tetrasaccharide related to the repeating unit of the O-antigen from Escherichia coli K-12
AU - Roy, Bimalendu
AU - Field, Robert A.
AU - Mukhopadhyay, Balaram
N1 - Funding Information: B.R. is thankful to the Council of Scientific and Industrial Research (CSIR), New Delhi, India, for a fellowship. The work is funded by the Department of Science and Technology (DST), New Delhi, India through a SERC Fast-Track Grant SR/FTP/CS-110/2005.
PY - 2009/11/23
Y1 - 2009/11/23
N2 - Synthesis of a tetrasaccharide related to the repeating unit of the O-antigen from Escherichia coli K-12 is reported in the form of its octyl glycoside. Syntheses of the 1,2-cis glycosidic linkages have been accomplished by using NIS in conjunction with H2SO4-silica, and it was found to be stereoselective and productive. The synthesized tetrasaccharide will be utilized as the substrate for galactofuranosyltransferase, WbbI.
AB - Synthesis of a tetrasaccharide related to the repeating unit of the O-antigen from Escherichia coli K-12 is reported in the form of its octyl glycoside. Syntheses of the 1,2-cis glycosidic linkages have been accomplished by using NIS in conjunction with H2SO4-silica, and it was found to be stereoselective and productive. The synthesized tetrasaccharide will be utilized as the substrate for galactofuranosyltransferase, WbbI.
KW - 1,2-Cis glycosylation
KW - Bacterial oligosaccharide
KW - HSO-silica
UR - http://www.scopus.com/inward/record.url?scp=70350780385&partnerID=8YFLogxK
U2 - 10.1016/j.carres.2009.09.026
DO - 10.1016/j.carres.2009.09.026
M3 - Article
C2 - 19836012
AN - SCOPUS:70350780385
SN - 0008-6215
VL - 344
SP - 2311
EP - 2316
JO - Carbohydrate Research
JF - Carbohydrate Research
IS - 17
ER -