Synthesis of two 'heteroaromatic rings of the future' for applications in medicinal chemistry

P. E. Silva Júnior, L. C D Rezende, Julia Possamai Gimenes, Vinícius Goncąlves Maltarollo, James Dale, G. H G Trossini, F. S. Emery, A. Ganesan

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


In a computational study, the 1H-pyrazolo[3,4-c]pyridin-5-ol and 2,6-naphthyridin-3-ol heterocycles were identified as unknown heteroaromatic ring systems of potential value for medicinal chemistry. Here we report robust and concise synthetic protocols that provide access to these two scaffolds on a multigram scale.

Original languageEnglish
Pages (from-to)22777-22780
Number of pages4
JournalRSC Advances
Issue number27
Publication statusPublished - 22 Feb 2016

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