Synthetic glycans, glycoarrays, and glyconanoparticles to investigate host infection by trypanosoma cruzi

Robert A. Field, Peterson Andrade, Vanessa L. Campo, Ivone Carvalho, Beatrice Y. M. Collet, Paul R. Crocker, Margherita Fais, Rositsa Karamanska, Balaram Mukhopadhayay, Sergey A. Nepogodiev, Abdul Rashid, Martin Rejzek, David A. Russell, Claire L. Schofield, Renate M. Van Well

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

Carbohydrate libraries, synthetic glycans and glycopeptides are contributing to understanding of the role of sialic acid recognition in host infection by the parasite Trypanosoma cruzi. Further, glycoarray approaches are allowing us to explore similarities and differences in the carbohydrate-binding specificity of host lectins while glyconanoparticles enable us to ask questions about the structure, sialylation and recognition of parasite mucins.

Original languageEnglish
Title of host publicationPetite and Sweet
Subtitle of host publicationGlyco-Nanotechnology as a Bridge to New Medicines
PublisherAmerican Chemical Society
Pages143-159
Number of pages17
ISBN (Print)9780841226883
DOIs
Publication statusPublished - 2011

Publication series

NameACS Symposium Series
Volume1091
ISSN (Print)0097-6156
ISSN (Electronic)1947-5918

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