Targeting higher-order DNA: Beyond the G-quadruplex

Lesley Howell; Mark Searcey

doi:10.1002/cbic.200900243

Targeting higher-order DNA: Beyond the G-quadruplex

Lesley Howell, Mark Searcey

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

There must be more to DNA than this: The G-quadruplex is a higher-order DNA structure that is of interest as a potential therapeutic target. However it is not the only structure to bind small-molecule ligands, and in this minireview we describe recent studies of molecules that target three-way and four-way junctions.

Original language	English
Pages (from-to)	2139-2143
Number of pages	5
Journal	ChemBioChem
Volume	10
Issue number	13
DOIs	https://doi.org/10.1002/cbic.200900243
Publication status	Published - Sept 2009

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10.1002/cbic.200900243

Cite this

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abstract = "There must be more to DNA than this: The G-quadruplex is a higher-order DNA structure that is of interest as a potential therapeutic target. However it is not the only structure to bind small-molecule ligands, and in this minireview we describe recent studies of molecules that target three-way and four-way junctions.",

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