Targeting higher-order DNA: Beyond the G-quadruplex

Lesley Howell; Mark Searcey

doi:10.1002/cbic.200900243

Targeting higher-order DNA: Beyond the G-quadruplex

Lesley Howell, Mark Searcey

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

There must be more to DNA than this: The G-quadruplex is a higher-order DNA structure that is of interest as a potential therapeutic target. However it is not the only structure to bind small-molecule ligands, and in this minireview we describe recent studies of molecules that target three-way and four-way junctions.

Original language	English
Pages (from-to)	2139-2143
Number of pages	5
Journal	ChemBioChem
Volume	10
Issue number	13
DOIs	https://doi.org/10.1002/cbic.200900243
Publication status	Published - Sep 2009

Access to Document

10.1002/cbic.200900243

Cite this

@article{1834f2fae31d4e8fb230212b36cb2754,

title = "Targeting higher-order DNA: Beyond the G-quadruplex",

abstract = "There must be more to DNA than this: The G-quadruplex is a higher-order DNA structure that is of interest as a potential therapeutic target. However it is not the only structure to bind small-molecule ligands, and in this minireview we describe recent studies of molecules that target three-way and four-way junctions.",

author = "Lesley Howell and Mark Searcey",

year = "2009",

month = sep,

doi = "10.1002/cbic.200900243",

language = "English",

volume = "10",

pages = "2139--2143",

journal = "ChemBioChem",

issn = "1439-4227",

publisher = "Wiley",

number = "13",

}

TY - JOUR

T1 - Targeting higher-order DNA: Beyond the G-quadruplex

AU - Howell, Lesley

AU - Searcey, Mark

PY - 2009/9

Y1 - 2009/9

N2 - There must be more to DNA than this: The G-quadruplex is a higher-order DNA structure that is of interest as a potential therapeutic target. However it is not the only structure to bind small-molecule ligands, and in this minireview we describe recent studies of molecules that target three-way and four-way junctions.

AB - There must be more to DNA than this: The G-quadruplex is a higher-order DNA structure that is of interest as a potential therapeutic target. However it is not the only structure to bind small-molecule ligands, and in this minireview we describe recent studies of molecules that target three-way and four-way junctions.

U2 - 10.1002/cbic.200900243

DO - 10.1002/cbic.200900243

M3 - Article

VL - 10

SP - 2139

EP - 2143

JO - ChemBioChem

JF - ChemBioChem

SN - 1439-4227

IS - 13

ER -