Tensile properties of Ag-EVOH electrospinning nanofiber mats for large muscle scaffolds

Chuanwei Zhang, Dandan Liu, Chao Xu, Dianzi Liu, Bin Wang

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1 Citation (Scopus)
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Abstract

Large muscle defect negatively influences people’s life, the common treatment is muscle transplantation but limited by donor source, large area wound, etc. Therefore, a muscle tissue scaffold with superimposed vascular network was developed. For ensuring the performance of fascia layer which alternated by poly(ethylene-co-vinyl alcohol) (EVOH) nanofiber mats encapsulated with Ag, the mechanical properties and water vapor transmission of different samples (7.5%, 10%, 12.5% EVOH solution densities with 0.02, 0.05, 0.08 g/ml of Ag, respectively) were mainly discussed. Meanwhile, the main parameters (voltage, tip-to-collector distance, solution density, concentration of Ag) were compared to find their influence on fabricating nanofibers.

Original languageEnglish
Pages (from-to)1312-1321
Number of pages10
JournalMechanics of Advanced Materials and Structures
Volume27
Issue number15
Early online date20 Nov 2018
DOIs
Publication statusPublished - 3 Aug 2020

Keywords

  • Large muscle defect
  • Young’s moduli
  • electrospinning
  • experimental parameters
  • nanofiber
  • strain rate
  • tensile properties
  • water vapor transmission

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