TGFbeta is active, and correlates with activators of TGFbeta, following porcine coronary angioplasty

Janet Chamberlain; Julian Gunn; Sheila E. Francis; Cathy M. Holt; Nadine D. Arnold; David C. Cumberland; Mark W. J. Ferguson; David C. Crossman

doi:10.1016/S0008-6363(01)00199-7

TGFbeta is active, and correlates with activators of TGFbeta, following porcine coronary angioplasty

Janet Chamberlain
, Julian Gunn
, Sheila E. Francis
, Cathy M. Holt
, Nadine D. Arnold
, David C. Cumberland
, Mark W. J. Ferguson
, David C. Crossman

Research output: Contribution to journal › Article

37 Citations (Scopus)

Abstract

We conclude that balloon injury causes an early rapid increase in levels of active TGFbeta, that correlates with the expression of TGFbeta activators. Thus, TGFbeta is a good potential target for anti-restenotic therapies.

Original language	English
Pages (from-to)	125-36
Number of pages	12
Journal	Cardiovascular Research
Volume	50
Issue number	1
DOIs	https://doi.org/10.1016/S0008-6363(01)00199-7
Publication status	Published - Apr 2001

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10.1016/S0008-6363(01)00199-7

Cite this

@article{dd834340503f4b3daa7c6312085fe7bd,

title = "TGFbeta is active, and correlates with activators of TGFbeta, following porcine coronary angioplasty",

abstract = "We conclude that balloon injury causes an early rapid increase in levels of active TGFbeta, that correlates with the expression of TGFbeta activators. Thus, TGFbeta is a good potential target for anti-restenotic therapies.",

author = "Janet Chamberlain and Julian Gunn and Francis, \{Sheila E.\} and Holt, \{Cathy M.\} and Arnold, \{Nadine D.\} and Cumberland, \{David C.\} and Ferguson, \{Mark W. J.\} and Crossman, \{David C.\}",

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AU - Chamberlain, Janet

AU - Gunn, Julian

AU - Francis, Sheila E.

AU - Holt, Cathy M.

AU - Arnold, Nadine D.

AU - Cumberland, David C.

AU - Ferguson, Mark W. J.

AU - Crossman, David C.

PY - 2001/4

Y1 - 2001/4

N2 - We conclude that balloon injury causes an early rapid increase in levels of active TGFbeta, that correlates with the expression of TGFbeta activators. Thus, TGFbeta is a good potential target for anti-restenotic therapies.

AB - We conclude that balloon injury causes an early rapid increase in levels of active TGFbeta, that correlates with the expression of TGFbeta activators. Thus, TGFbeta is a good potential target for anti-restenotic therapies.

U2 - 10.1016/S0008-6363(01)00199-7

DO - 10.1016/S0008-6363(01)00199-7

M3 - Article

SN - 0008-6363

VL - 50

SP - 125

EP - 136

JO - Cardiovascular Research

JF - Cardiovascular Research

IS - 1

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