The basic science of bone marrow aspirate concentrate in chondral injuries

James Holton, Mohamed Imam, Jonathan Ward, Martyn Snow

Research output: Contribution to journalArticle

35 Citations (Scopus)
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Abstract

There has been great interest in bone marrow aspirate concentrate (BMAC) as a cost effective method in delivering mesenchymal stem cells (MSCs) to aid in the repair and regeneration of cartilage defects. Alongside MSCs, BMAC contains a range of growth factors and cytokines to support cell growth following injury. However, there is paucity of information relating to the basic science underlying BMAC and its exact biological role in supporting the growth and regeneration of chondrocytes. The focus of this review is the basic science underlying BMAC in relation to chondral damage and regeneration.
Original languageEnglish
Article number6659
JournalOrthopedic Reviews
Volume8
DOIs
Publication statusPublished - 30 Sep 2016

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