The Cambridge Semantic Test Battery: Detection of semantic deficits in patients with semantic dementia and Alzheimer's disease

Anna-Lynne R. Adlam, Karalyn Patterson, Sasha Bozeat, John R. Hodges

Research output: Contribution to journalArticlepeer-review

87 Citations (Scopus)

Abstract

The aims of this study were (a) to explore the utility of, and make more widely available, an updated and extended version of the Cambridge Semantic Memory test battery, and (b) to use this battery in conjunction with other tests to characterise the profile of several different forms of progressive cognitive impairment: semantic dementia (SD, n?=?15), mild cognitive impairment (MCI, n?=?7), established Alzheimer's disease (AD) (n?=?8), all in comparison to normal controls (n?=?45). The semantic battery is useful in a variety of ways for exploring the nature of semantic deficits; on its own, however, it does not provide sensitive differentiation between patients with AD and SD. An assessment including measures of episodic memory and visuospatial abilities as well as the semantic battery is recommended for good characterisation of the cognitive profiles associated with SD and AD.
Original languageEnglish
Pages (from-to)193-207
Number of pages15
JournalNeurocase
Volume16
Issue number3
DOIs
Publication statusPublished - Jun 2010

Keywords

  • Language Tests
  • Animals
  • Humans
  • Alzheimer Disease
  • Aged
  • Cognition Disorders
  • Semantics
  • Memory
  • Frontotemporal Lobar Degeneration
  • Aged, 80 and over
  • Adult
  • Middle Aged
  • Neuropsychological Tests
  • Female
  • Male

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