Abstract
Original language | English |
---|---|
Pages (from-to) | 623-632 |
Number of pages | 10 |
Journal | British Journal of Nutrition |
Volume | 94 |
Issue number | 5 |
DOIs | |
Publication status | Published - Nov 2005 |
Keywords
- Animals
- Disease Models, Animal
- Eating
- Environment
- Genetic Variation
- Genome, Human
- Genomics
- Humans
- International Cooperation
- Nutritional Physiological Phenomena
- Phenotype
- Research
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The case for strategic international alliances to harness nutritional genomics for public and personal health. / Kaput, Jim; Ordovas, Jose M; Ferguson, Lynnette; van Ommen, Ben; Rodriguez, Raymond L; Allen, Lindsay; Ames, Bruce N; Dawson, Kevin; German, Bruce; Krauss, Ronald; Malyj, Wasyl; Archer, Michael C; Barnes, Stephen; Bartholomew, Amelia; Birk, Ruth; van Bladeren, Peter; Bradford, Kent J; Brown, Kenneth H; Caetano, Rosane; Castle, David; Chadwick, Ruth; Clarke, Stephen; Clément, Karine; Cooney, Craig A; Corella, Dolores; Manica da Cruz, Ivana Beatrice; Daniel, Hannelore; Duster, Troy; Ebbesson, Sven O E; Elliott, Ruan; Fairweather-Tait, Susan; Felton, Jim; Fenech, Michael; Finley, John W; Fogg-Johnson, Nancy; Gill-Garrison, Rosalynn; Gibney, Michael J; Gillies, Peter J; Gustafsson, Jan-Ake; Hartman, John L; He, Lin; Hwang, Jae-Kwan; Jais, Jean-Philippe; Jang, Yangsoo; Joost, Hans; Junien, Claudine; Kanter, Mitchell; Kibbe, Warren A; Koletzko, Berthold; Korf, Bruce R; Kornman, Kenneth; Krempin, David W; Langin, Dominique; Lauren, Denis R; Ho Lee, Jong; Leveille, Gilbert A; Lin, Su-Ju; Mathers, John; Mayne, Michael; McNabb, Warren; Milner, John A; Morgan, Peter; Muller, Michael; Nikolsky, Yuri; van der Ouderaa, Frans; Park, Taesun; Pensel, Norma; Perez-Jimenez, Francisco; Poutanen, Kaisa; Roberts, Matthew; Saris, Wim H M; Schuster, Gertrud; Shelling, Andrew N; Simopoulos, Artemis P; Southon, Sue; Tai, E Shyong; Towne, Bradford; Trayhurn, Paul; Uauy, Ricardo; Visek, Willard J; Warden, Craig; Weiss, Rick; Wiencke, John; Winkler, Jack; Wolff, George L; Zhao-Wilson, Xi; Zucker, Jean-Daniel.
In: British Journal of Nutrition, Vol. 94, No. 5, 11.2005, p. 623-632.Research output: Contribution to journal › Article › peer-review
TY - JOUR
T1 - The case for strategic international alliances to harness nutritional genomics for public and personal health
AU - Kaput, Jim
AU - Ordovas, Jose M
AU - Ferguson, Lynnette
AU - van Ommen, Ben
AU - Rodriguez, Raymond L
AU - Allen, Lindsay
AU - Ames, Bruce N
AU - Dawson, Kevin
AU - German, Bruce
AU - Krauss, Ronald
AU - Malyj, Wasyl
AU - Archer, Michael C
AU - Barnes, Stephen
AU - Bartholomew, Amelia
AU - Birk, Ruth
AU - van Bladeren, Peter
AU - Bradford, Kent J
AU - Brown, Kenneth H
AU - Caetano, Rosane
AU - Castle, David
AU - Chadwick, Ruth
AU - Clarke, Stephen
AU - Clément, Karine
AU - Cooney, Craig A
AU - Corella, Dolores
AU - Manica da Cruz, Ivana Beatrice
AU - Daniel, Hannelore
AU - Duster, Troy
AU - Ebbesson, Sven O E
AU - Elliott, Ruan
AU - Fairweather-Tait, Susan
AU - Felton, Jim
AU - Fenech, Michael
AU - Finley, John W
AU - Fogg-Johnson, Nancy
AU - Gill-Garrison, Rosalynn
AU - Gibney, Michael J
AU - Gillies, Peter J
AU - Gustafsson, Jan-Ake
AU - Hartman, John L
AU - He, Lin
AU - Hwang, Jae-Kwan
AU - Jais, Jean-Philippe
AU - Jang, Yangsoo
AU - Joost, Hans
AU - Junien, Claudine
AU - Kanter, Mitchell
AU - Kibbe, Warren A
AU - Koletzko, Berthold
AU - Korf, Bruce R
AU - Kornman, Kenneth
AU - Krempin, David W
AU - Langin, Dominique
AU - Lauren, Denis R
AU - Ho Lee, Jong
AU - Leveille, Gilbert A
AU - Lin, Su-Ju
AU - Mathers, John
AU - Mayne, Michael
AU - McNabb, Warren
AU - Milner, John A
AU - Morgan, Peter
AU - Muller, Michael
AU - Nikolsky, Yuri
AU - van der Ouderaa, Frans
AU - Park, Taesun
AU - Pensel, Norma
AU - Perez-Jimenez, Francisco
AU - Poutanen, Kaisa
AU - Roberts, Matthew
AU - Saris, Wim H M
AU - Schuster, Gertrud
AU - Shelling, Andrew N
AU - Simopoulos, Artemis P
AU - Southon, Sue
AU - Tai, E Shyong
AU - Towne, Bradford
AU - Trayhurn, Paul
AU - Uauy, Ricardo
AU - Visek, Willard J
AU - Warden, Craig
AU - Weiss, Rick
AU - Wiencke, John
AU - Winkler, Jack
AU - Wolff, George L
AU - Zhao-Wilson, Xi
AU - Zucker, Jean-Daniel
PY - 2005/11
Y1 - 2005/11
N2 - Nutrigenomics is the study of how constituents of the diet interact with genes, and their products, to alter phenotype and, conversely, how genes and their products metabolise these constituents into nutrients, antinutrients, and bioactive compounds. Results from molecular and genetic epidemiological studies indicate that dietary unbalance can alter gene-nutrient interactions in ways that increase the risk of developing chronic disease. The interplay of human genetic variation and environmental factors will make identifying causative genes and nutrients a formidable, but not intractable, challenge. We provide specific recommendations for how to best meet this challenge and discuss the need for new methodologies and the use of comprehensive analyses of nutrient-genotype interactions involving large and diverse populations. The objective of the present paper is to stimulate discourse and collaboration among nutrigenomic researchers and stakeholders, a process that will lead to an increase in global health and wellness by reducing health disparities in developed and developing countries.
AB - Nutrigenomics is the study of how constituents of the diet interact with genes, and their products, to alter phenotype and, conversely, how genes and their products metabolise these constituents into nutrients, antinutrients, and bioactive compounds. Results from molecular and genetic epidemiological studies indicate that dietary unbalance can alter gene-nutrient interactions in ways that increase the risk of developing chronic disease. The interplay of human genetic variation and environmental factors will make identifying causative genes and nutrients a formidable, but not intractable, challenge. We provide specific recommendations for how to best meet this challenge and discuss the need for new methodologies and the use of comprehensive analyses of nutrient-genotype interactions involving large and diverse populations. The objective of the present paper is to stimulate discourse and collaboration among nutrigenomic researchers and stakeholders, a process that will lead to an increase in global health and wellness by reducing health disparities in developed and developing countries.
KW - Animals
KW - Disease Models, Animal
KW - Eating
KW - Environment
KW - Genetic Variation
KW - Genome, Human
KW - Genomics
KW - Humans
KW - International Cooperation
KW - Nutritional Physiological Phenomena
KW - Phenotype
KW - Research
U2 - 10.1079/BJN20051585
DO - 10.1079/BJN20051585
M3 - Article
C2 - 16277761
VL - 94
SP - 623
EP - 632
JO - British Journal of Nutrition
JF - British Journal of Nutrition
SN - 0007-1145
IS - 5
ER -