The conserved AvrE family of bacterial effectors: Functions and targets during pathogenesis

Laura Herold, Sera Choi, Sheng Yang He, Cyril Zipfel

Research output: Contribution to journalReview articlepeer-review

Abstract

The AvrE family of type III secreted effectors are highly conserved among many agriculturally important phytopathogenic bacteria. Despite their critical roles in the pathogenesis of phytopathogenic bacteria, the molecular functions and virulence mechanisms of these effectors have been largely unknown. However, recent studies have identified host-interacting proteins and demonstrated that AvrE family effectors can form water-permeable channels in the plant plasma membrane (PM) to create a hydrated and nutrient-rich extracellular space (apoplast) required for disease establishment. Here, we summarize these recent discoveries and highlight open questions related to AvrE-targeted host proteins.
Original languageEnglish
Pages (from-to)184-193
Number of pages10
JournalTrends in Microbiology
Volume33
Issue number2
Early online date14 Sept 2024
DOIs
Publication statusPublished - 4 Feb 2025

Keywords

  • abscisic acid
  • apoplast hydration
  • bacteria
  • channel
  • pathogenesis
  • receptor kinases/protein phosphatases
  • type III secreted effector
  • virulence effector

Cite this