Abstract
DynDom3D is a program for the analysis of domain movements in multimeric proteins. Its input is two structure files that indicate a possible domain movement, but the onus has been on the user to process the files so that there is the necessary one-to-one equivalence between atoms in the two atom lists. This is often a prohibitive task to carry out manually which has limited the application of DynDom3D. Here we report on a webserver with a pre-processor that automatically creates an equivalence between atoms using sequence alignment methods. The processed structure files are passed to DynDom3D and the results are presented on a webpage that includes molecular graphics for easy visualization. The website can be found at: http://www.cmp.uea.ac.uk/dyndom/3D
| Original language | English |
|---|---|
| Pages (from-to) | 21-26 |
| Number of pages | 6 |
| Journal | Journal of Computational Biology |
| Volume | 23 |
| Issue number | 1 |
| Early online date | 5 Nov 2015 |
| DOIs | |
| Publication status | Published - 31 Dec 2015 |
Profiles
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Steven Hayward
- School of Computing Sciences - Professor of Computational Biology
- Centre for Japanese Studies - Member
- Computational Biology - Member
Person: Research Group Member, Research Centre Member, Academic, Teaching & Research