@article{5e5f145113c44ef4a24d4312fbafa313,
title = "The effect of perhexiline on myocardial protection during coronary artery surgery: A two-centre, randomized, double-blind, placebo-controlled trial",
abstract = "Perhexiline is thought to modulate metabolism by inhibiting mitochondrial carnitine palmitoyltransferase-1, reducing fatty acid uptake and increasing carbohydrate utilization. This study assessed whether preoperative perhexiline improves markers of myocardial protection in patients undergoing coronary artery bypass graft surgery and analysed its effect on the myocardial metabolome.",
author = "Drury, {Nigel E.} and Howell, {Neil J.} and Calvert, {Melanie J.} and Weber, {Ralf J. M.} and Senanayake, {Eshan L.} and Lewis, {Michael E.} and Hyde, {Jonathan A. J.} and Green, {David H.} and Mascaro, {Jorge G.} and Wilson, {Ian C.} and Graham, {Timothy R.} and Rooney, {Stephen J.} and Viant, {Mark R.} and Nick Freemantle and Frenneaux, {Michael P.} and Domenico Pagano and investigators",
note = "{\textcopyright} The Author 2014. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact
[email protected]",
year = "2015",
month = mar,
doi = "10.1093/ejcts/ezu238",
language = "English",
volume = "47",
pages = "464--472",
journal = "European Journal of Cardio-Thoracic Surgery",
issn = "1010-7940",
publisher = "Oxford University Press",
number = "3",
}