The Effect of Short-Term Vitamin D Supplementation on Calcium Status in Vitamin D Insufficient Renal Transplant Recipients at Risk of Hypercalcaemia

Irene Lynch Cronin, Fiona Byrne, Ross Doyle, William D. Fraser, Allison Chipchase, Joseph A. Eustace

Research output: Contribution to journalArticle

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Abstract

Vitamin D insufficiency is highly prevalent amongst renal transplant recipients and in observational studies is associated with adverse outcomes. Hypercalcaemia, usually due to persistent hyperparathyroidism, also commonly occurs in this population and often coexists with vitamin D insufficiency. However, concern that vitamin D supplementation might exacerbate the pre-existing hypercalcaemia often leads clinicians to avoid vitamin D supplementation in such patients. This feasibility study aimed to quantify the effect on serum calcium of short-term low- dose cholecalciferol supplementation in a group of renal transplant recipients with a recent history of serum calcium levels >10 mg/dL.
Original languageEnglish
Pages (from-to)181-187
Number of pages7
JournalJournal of Renal Nutrition
Volume29
Issue number3
Early online date25 Jan 2019
DOIs
Publication statusPublished - May 2019

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