The efficient synthesis of alkoxy-esters from hydroxy carboxylic acids using dimsyllithium in dimethylsulfoxide followed by alkylation with an alkyl halide

Philip Bulman Page; YH Chan; H Heaney; MJ McGrath; E Moreno

doi:10.1055/s-2004-834827

The efficient synthesis of alkoxy-esters from hydroxy carboxylic acids using dimsyllithium in dimethylsulfoxide followed by alkylation with an alkyl halide

Philip Bulman Page
, YH Chan
, H Heaney
, MJ McGrath
, E Moreno

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Hydroxy acids are converted directly into the related alkyl ether-alkyl esters in high yields in a single operation by double deprotonation using dimsyllithium in dimethylsulfoxide followed by treatment with an alkyl halide.

Original language	English
Pages (from-to)	2606-2608
Number of pages	3
Journal	Synlett
Issue number	14
DOIs	https://doi.org/10.1055/s-2004-834827
Publication status	Published - 22 Nov 2004

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10.1055/s-2004-834827

Cite this

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title = "The efficient synthesis of alkoxy-esters from hydroxy carboxylic acids using dimsyllithium in dimethylsulfoxide followed by alkylation with an alkyl halide",

abstract = "Hydroxy acids are converted directly into the related alkyl ether-alkyl esters in high yields in a single operation by double deprotonation using dimsyllithium in dimethylsulfoxide followed by treatment with an alkyl halide.",

author = "\{Bulman Page\}, Philip and YH Chan and H Heaney and MJ McGrath and E Moreno",

year = "2004",

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AU - Bulman Page, Philip

AU - Chan, YH

AU - Heaney, H

AU - McGrath, MJ

AU - Moreno, E

PY - 2004/11/22

Y1 - 2004/11/22

N2 - Hydroxy acids are converted directly into the related alkyl ether-alkyl esters in high yields in a single operation by double deprotonation using dimsyllithium in dimethylsulfoxide followed by treatment with an alkyl halide.

AB - Hydroxy acids are converted directly into the related alkyl ether-alkyl esters in high yields in a single operation by double deprotonation using dimsyllithium in dimethylsulfoxide followed by treatment with an alkyl halide.

U2 - 10.1055/s-2004-834827

DO - 10.1055/s-2004-834827

M3 - Article

SN - 0936-5214

SP - 2606

EP - 2608

JO - Synlett

JF - Synlett

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