The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription

Alper Akay; Tomas Di Domenico; Kin M. Suen; Amena Nabih; Guillermo E. Parada; Mark Larance; Ragini Medhi; Ahmet C. Berkyurek; Xinlian Zhang; Christopher J. Wedeles; Konrad L.m. Rudolph; Jan Engelhardt; Martin Hemberg; Ping Ma; Angus I. Lamond; Julie M. Claycomb; Eric A. Miska

doi:10.1016/j.devcel.2017.07.002

The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription

Alper Akay, Tomas Di Domenico, Kin M. Suen, Amena Nabih, Guillermo E. Parada, Mark Larance, Ragini Medhi, Ahmet C. Berkyurek, Xinlian Zhang, Christopher J. Wedeles, Konrad L.m. Rudolph, Jan Engelhardt, Martin Hemberg, Ping Ma, Angus I. Lamond, Julie M. Claycomb, Eric A. Miska

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Original language	English
Pages (from-to)	241-255.e6
Journal	Developmental Cell
Volume	42
Issue number	3
Early online date	7 Aug 2017
DOIs	https://doi.org/10.1016/j.devcel.2017.07.002
Publication status	Published - 7 Aug 2017

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Helicase_Aquarius-EMB-4_2017Final published version, 29.3 MBLicence: CC BY

https://www.repository.cam.ac.uk/handle/1810/265382Licence: CC BY

Alper Akay
- A.Akayuea.acuk
- School of Biological Sciences - UKRI Future Leaders Fellow
- Cells and Tissues - Member
- RNA (epi)Genetics Lab - Group Lead
Person: Group Lead, Research Group Member, Academic, Teaching & Research

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Akay, A., Di Domenico, T., Suen, K. M., Nabih, A., Parada, G. E., Larance, M., Medhi, R., Berkyurek, A. C., Zhang, X., Wedeles, C. J., Rudolph, K. L. M., Engelhardt, J., Hemberg, M., Ma, P., Lamond, A. I., Claycomb, J. M., & Miska, E. A. (2017). The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription. Developmental Cell, 42(3), 241-255.e6. https://doi.org/10.1016/j.devcel.2017.07.002

Akay, Alper ; Di Domenico, Tomas ; Suen, Kin M. ; Nabih, Amena ; Parada, Guillermo E. ; Larance, Mark ; Medhi, Ragini ; Berkyurek, Ahmet C. ; Zhang, Xinlian ; Wedeles, Christopher J. ; Rudolph, Konrad L.m. ; Engelhardt, Jan ; Hemberg, Martin ; Ma, Ping ; Lamond, Angus I. ; Claycomb, Julie M. ; Miska, Eric A. / The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription. In: Developmental Cell. 2017 ; Vol. 42, No. 3. pp. 241-255.e6.

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title = "The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription",

author = "Alper Akay and {Di Domenico}, Tomas and Suen, {Kin M.} and Amena Nabih and Parada, {Guillermo E.} and Mark Larance and Ragini Medhi and Berkyurek, {Ahmet C.} and Xinlian Zhang and Wedeles, {Christopher J.} and Rudolph, {Konrad L.m.} and Jan Engelhardt and Martin Hemberg and Ping Ma and Lamond, {Angus I.} and Claycomb, {Julie M.} and Miska, {Eric A.}",

year = "2017",

month = aug,

day = "7",

doi = "10.1016/j.devcel.2017.07.002",

language = "English",

volume = "42",

pages = "241--255.e6",

journal = "Developmental Cell",

issn = "1534-5807",

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Akay, A, Di Domenico, T, Suen, KM, Nabih, A, Parada, GE, Larance, M, Medhi, R, Berkyurek, AC, Zhang, X, Wedeles, CJ, Rudolph, KLM, Engelhardt, J, Hemberg, M, Ma, P, Lamond, AI, Claycomb, JM & Miska, EA 2017, 'The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription', Developmental Cell, vol. 42, no. 3, pp. 241-255.e6. https://doi.org/10.1016/j.devcel.2017.07.002

The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription. / Akay, Alper; Di Domenico, Tomas; Suen, Kin M.; Nabih, Amena; Parada, Guillermo E.; Larance, Mark; Medhi, Ragini; Berkyurek, Ahmet C.; Zhang, Xinlian; Wedeles, Christopher J.; Rudolph, Konrad L.m.; Engelhardt, Jan; Hemberg, Martin; Ma, Ping; Lamond, Angus I.; Claycomb, Julie M.; Miska, Eric A.

In: Developmental Cell, Vol. 42, No. 3, 07.08.2017, p. 241-255.e6.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription

AU - Akay, Alper

AU - Di Domenico, Tomas

AU - Suen, Kin M.

AU - Nabih, Amena

AU - Parada, Guillermo E.

AU - Larance, Mark

AU - Medhi, Ragini

AU - Berkyurek, Ahmet C.

AU - Zhang, Xinlian

AU - Wedeles, Christopher J.

AU - Rudolph, Konrad L.m.

AU - Engelhardt, Jan

AU - Hemberg, Martin

AU - Ma, Ping

AU - Lamond, Angus I.

AU - Claycomb, Julie M.

AU - Miska, Eric A.

PY - 2017/8/7

Y1 - 2017/8/7

U2 - 10.1016/j.devcel.2017.07.002

DO - 10.1016/j.devcel.2017.07.002

M3 - Article

VL - 42

SP - 241-255.e6

JO - Developmental Cell

JF - Developmental Cell

SN - 1534-5807

IS - 3

ER -

The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription

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Alper Akay

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