The highly diastereoselective synthesis of oxazolidines derived from ketones and pseudoephedrine or ephedrine

Benjamin R. Buckley, Philip C. Bulman Page, Mark Edgar, Mark R. J. Elsegood, Colin M. Hayman, Harry Heaney, Gerasimos A. Rassias, Salem A. Talib, John Liddle, Simon A. Readshaw, Christopher J. Seaman

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

2,2-Dialkyl-3,4-dimethyl-5-phenyloxazolidines and 2-alkyl-2-aryl-3,4-dimethyl-5-phenyloxazolidines are formed with high diastereoselectivity from ketones and pseudoephedrine or ephedrine in the presence of scandium triflate and 4 A molecular sieves.
Original languageEnglish
Pages (from-to)971-975
Number of pages5
JournalSynlett
Issue number6
DOIs
Publication statusPublished - 2005

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