The highly diastereoselective synthesis of oxazolidines derived from ketones and pseudoephedrine or ephedrine

Benjamin R. Buckley; Philip C. Bulman Page; Mark Edgar; Mark R. J. Elsegood; Colin M. Hayman; Harry Heaney; Gerasimos A. Rassias; Salem A. Talib; John Liddle; Simon A. Readshaw; Christopher J. Seaman

doi:10.1055/s-2005-864824

The highly diastereoselective synthesis of oxazolidines derived from ketones and pseudoephedrine or ephedrine

Benjamin R. Buckley, Philip C. Bulman Page, Mark Edgar, Mark R. J. Elsegood, Colin M. Hayman, Harry Heaney, Gerasimos A. Rassias, Salem A. Talib, John Liddle, Simon A. Readshaw, Christopher J. Seaman

Chemistry of Materials and Catalysis

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

2,2-Dialkyl-3,4-dimethyl-5-phenyloxazolidines and 2-alkyl-2-aryl-3,4-dimethyl-5-phenyloxazolidines are formed with high diastereoselectivity from ketones and pseudoephedrine or ephedrine in the presence of scandium triflate and 4 A molecular sieves.

Original language	English
Pages (from-to)	971-975
Number of pages	5
Journal	Synlett
Issue number	6
DOIs	https://doi.org/10.1055/s-2005-864824
Publication status	Published - 2005

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10.1055/s-2005-864824

Cite this

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title = "The highly diastereoselective synthesis of oxazolidines derived from ketones and pseudoephedrine or ephedrine",

abstract = "2,2-Dialkyl-3,4-dimethyl-5-phenyloxazolidines and 2-alkyl-2-aryl-3,4-dimethyl-5-phenyloxazolidines are formed with high diastereoselectivity from ketones and pseudoephedrine or ephedrine in the presence of scandium triflate and 4 A molecular sieves.",

author = "Buckley, {Benjamin R.} and {Bulman Page}, {Philip C.} and Mark Edgar and Elsegood, {Mark R. J.} and Hayman, {Colin M.} and Harry Heaney and Rassias, {Gerasimos A.} and Talib, {Salem A.} and John Liddle and Readshaw, {Simon A.} and Seaman, {Christopher J.}",

year = "2005",

doi = "10.1055/s-2005-864824",

language = "English",

pages = "971--975",

journal = "Synlett",

issn = "0936-5214",

publisher = "Georg Thieme Verlag",

number = "6",

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TY - JOUR

T1 - The highly diastereoselective synthesis of oxazolidines derived from ketones and pseudoephedrine or ephedrine

AU - Buckley, Benjamin R.

AU - Bulman Page, Philip C.

AU - Edgar, Mark

AU - Elsegood, Mark R. J.

AU - Hayman, Colin M.

AU - Heaney, Harry

AU - Rassias, Gerasimos A.

AU - Talib, Salem A.

AU - Liddle, John

AU - Readshaw, Simon A.

AU - Seaman, Christopher J.

PY - 2005

Y1 - 2005

N2 - 2,2-Dialkyl-3,4-dimethyl-5-phenyloxazolidines and 2-alkyl-2-aryl-3,4-dimethyl-5-phenyloxazolidines are formed with high diastereoselectivity from ketones and pseudoephedrine or ephedrine in the presence of scandium triflate and 4 A molecular sieves.

AB - 2,2-Dialkyl-3,4-dimethyl-5-phenyloxazolidines and 2-alkyl-2-aryl-3,4-dimethyl-5-phenyloxazolidines are formed with high diastereoselectivity from ketones and pseudoephedrine or ephedrine in the presence of scandium triflate and 4 A molecular sieves.

U2 - 10.1055/s-2005-864824

DO - 10.1055/s-2005-864824

M3 - Article

SP - 971

EP - 975

JO - Synlett

JF - Synlett

SN - 0936-5214

IS - 6

ER -