The leucine-rich repeat receptor kinase BIR2 is a negative regulator of BAK1 in plant immunity

Thierry Halter; Julia Imkampe; Sara Mazzotta; Michael Wierzba; Sandra Postel; Christoph Bücherl; Christian Kiefer; Mark Stahl; Delphine Chinchilla; Xiaofeng Wang; Thorsten Nürnberger; Cyril Zipfel; Steven Clouse; Jan Willem Borst; Sjef Boeren; Sacco C de Vries; Frans Tax; Birgit Kemmerling

doi:10.1016/j.cub.2013.11.047

The leucine-rich repeat receptor kinase BIR2 is a negative regulator of BAK1 in plant immunity

Thierry Halter, Julia Imkampe, Sara Mazzotta, Michael Wierzba, Sandra Postel, Christoph Bücherl, Christian Kiefer, Mark Stahl, Delphine Chinchilla, Xiaofeng Wang, Thorsten Nürnberger, Cyril Zipfel, Steven Clouse, Jan Willem Borst, Sjef Boeren, Sacco C de Vries, Frans Tax, Birgit Kemmerling

Research output: Contribution to journal › Article › peer-review

201 Citations (Scopus)

Abstract

Transmembrane leucine-rich repeat (LRR) receptors are commonly used innate immune receptors in plants and animals but can also sense endogenous signals to regulate development. BAK1 is a plant LRR-receptor-like kinase (RLK) that interacts with several ligand-binding LRR-RLKs to positively regulate their functions. BAK1 is involved in brassinosteroid-dependent growth and development, innate immunity, and cell-death control by interacting with the brassinosteroid receptor BRI1, immune receptors, such as FLS2 and EFR, and the small receptor kinase BIR1, respectively.

Original language	English
Pages (from-to)	134-143
Number of pages	10
Journal	Current Biology
Volume	24
Issue number	2
DOIs	https://doi.org/10.1016/j.cub.2013.11.047
Publication status	Published - 20 Jan 2014

Access to Document

10.1016/j.cub.2013.11.047

Cyril Zipfel
- C.Zipfeluea.acuk
- The Sainsbury Laboratory - Senior Scientist (TSL)
- Plant Sciences - Member
Person: Research Group Member, Academic, Teaching & Research

Cite this

Halter, T., Imkampe, J., Mazzotta, S., Wierzba, M., Postel, S., Bücherl, C., Kiefer, C., Stahl, M., Chinchilla, D., Wang, X., Nürnberger, T., Zipfel, C., Clouse, S., Borst, J. W., Boeren, S., de Vries, S. C., Tax, F., & Kemmerling, B. (2014). The leucine-rich repeat receptor kinase BIR2 is a negative regulator of BAK1 in plant immunity. Current Biology, 24(2), 134-143. https://doi.org/10.1016/j.cub.2013.11.047

Halter, Thierry ; Imkampe, Julia ; Mazzotta, Sara ; Wierzba, Michael ; Postel, Sandra ; Bücherl, Christoph ; Kiefer, Christian ; Stahl, Mark ; Chinchilla, Delphine ; Wang, Xiaofeng ; Nürnberger, Thorsten ; Zipfel, Cyril ; Clouse, Steven ; Borst, Jan Willem ; Boeren, Sjef ; de Vries, Sacco C ; Tax, Frans ; Kemmerling, Birgit. / The leucine-rich repeat receptor kinase BIR2 is a negative regulator of BAK1 in plant immunity. In: Current Biology. 2014 ; Vol. 24, No. 2. pp. 134-143.

@article{a45261e8e3f84afcba112b0b9f86c769,

title = "The leucine-rich repeat receptor kinase BIR2 is a negative regulator of BAK1 in plant immunity",

abstract = "Transmembrane leucine-rich repeat (LRR) receptors are commonly used innate immune receptors in plants and animals but can also sense endogenous signals to regulate development. BAK1 is a plant LRR-receptor-like kinase (RLK) that interacts with several ligand-binding LRR-RLKs to positively regulate their functions. BAK1 is involved in brassinosteroid-dependent growth and development, innate immunity, and cell-death control by interacting with the brassinosteroid receptor BRI1, immune receptors, such as FLS2 and EFR, and the small receptor kinase BIR1, respectively.",

author = "Thierry Halter and Julia Imkampe and Sara Mazzotta and Michael Wierzba and Sandra Postel and Christoph B{\"u}cherl and Christian Kiefer and Mark Stahl and Delphine Chinchilla and Xiaofeng Wang and Thorsten N{\"u}rnberger and Cyril Zipfel and Steven Clouse and Borst, {Jan Willem} and Sjef Boeren and {de Vries}, {Sacco C} and Frans Tax and Birgit Kemmerling",

year = "2014",

month = jan,

day = "20",

doi = "10.1016/j.cub.2013.11.047",

language = "English",

volume = "24",

pages = "134--143",

journal = "Current Biology",

issn = "0960-9822",

publisher = "Cell Press",

number = "2",

}

Halter, T, Imkampe, J, Mazzotta, S, Wierzba, M, Postel, S, Bücherl, C, Kiefer, C, Stahl, M, Chinchilla, D, Wang, X, Nürnberger, T, Zipfel, C, Clouse, S, Borst, JW, Boeren, S, de Vries, SC, Tax, F & Kemmerling, B 2014, 'The leucine-rich repeat receptor kinase BIR2 is a negative regulator of BAK1 in plant immunity', Current Biology, vol. 24, no. 2, pp. 134-143. https://doi.org/10.1016/j.cub.2013.11.047

The leucine-rich repeat receptor kinase BIR2 is a negative regulator of BAK1 in plant immunity. / Halter, Thierry; Imkampe, Julia; Mazzotta, Sara; Wierzba, Michael; Postel, Sandra; Bücherl, Christoph; Kiefer, Christian; Stahl, Mark; Chinchilla, Delphine; Wang, Xiaofeng; Nürnberger, Thorsten; Zipfel, Cyril; Clouse, Steven; Borst, Jan Willem; Boeren, Sjef; de Vries, Sacco C; Tax, Frans; Kemmerling, Birgit.

In: Current Biology, Vol. 24, No. 2, 20.01.2014, p. 134-143.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - The leucine-rich repeat receptor kinase BIR2 is a negative regulator of BAK1 in plant immunity

AU - Halter, Thierry

AU - Imkampe, Julia

AU - Mazzotta, Sara

AU - Wierzba, Michael

AU - Postel, Sandra

AU - Bücherl, Christoph

AU - Kiefer, Christian

AU - Stahl, Mark

AU - Chinchilla, Delphine

AU - Wang, Xiaofeng

AU - Nürnberger, Thorsten

AU - Zipfel, Cyril

AU - Clouse, Steven

AU - Borst, Jan Willem

AU - Boeren, Sjef

AU - de Vries, Sacco C

AU - Tax, Frans

AU - Kemmerling, Birgit

PY - 2014/1/20

Y1 - 2014/1/20

N2 - Transmembrane leucine-rich repeat (LRR) receptors are commonly used innate immune receptors in plants and animals but can also sense endogenous signals to regulate development. BAK1 is a plant LRR-receptor-like kinase (RLK) that interacts with several ligand-binding LRR-RLKs to positively regulate their functions. BAK1 is involved in brassinosteroid-dependent growth and development, innate immunity, and cell-death control by interacting with the brassinosteroid receptor BRI1, immune receptors, such as FLS2 and EFR, and the small receptor kinase BIR1, respectively.

AB - Transmembrane leucine-rich repeat (LRR) receptors are commonly used innate immune receptors in plants and animals but can also sense endogenous signals to regulate development. BAK1 is a plant LRR-receptor-like kinase (RLK) that interacts with several ligand-binding LRR-RLKs to positively regulate their functions. BAK1 is involved in brassinosteroid-dependent growth and development, innate immunity, and cell-death control by interacting with the brassinosteroid receptor BRI1, immune receptors, such as FLS2 and EFR, and the small receptor kinase BIR1, respectively.

U2 - 10.1016/j.cub.2013.11.047

DO - 10.1016/j.cub.2013.11.047

M3 - Article

C2 - 24388849

VL - 24

SP - 134

EP - 143

JO - Current Biology

JF - Current Biology

SN - 0960-9822

IS - 2

ER -

The leucine-rich repeat receptor kinase BIR2 is a negative regulator of BAK1 in plant immunity

Abstract

Access to Document

Profiles

Cyril Zipfel

Cite this