The MACRO Trial: defining best management of chronic rhinosinusitis

Gabija Klyvyte, Carl Philpott, Claire Hopkins

Research output: Contribution to journal › Review article

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Original language	English
Journal	ENT News
Publication status	Published - 8 Jan 2026

Keywords

chronic rhinosinusitis
endoscopic sinus surgery

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rba13-Philpott_etal_The_MACRO_tFinal published version, 205 KBLicence: CC BY-NC-ND

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https://www.entandaudiologynews.com/features/ent-features/post/the-macro-trial-defining-best-management-of-chronic-rhinosinusitis

1 Finished

Defining best Management for Adults with Chronic RhinOsinusitis: the MACRO Programme
Philpott, C. & Howard Wilsher, S.
National Institute for Health and Care Research
1/11/16 → 31/12/25
Project: Research

1 Article

The clinical effectiveness of clarithromycin versus endoscopic sinus surgery for adults with chronic rhinosinusitis with and without nasal polyps (MACRO): A pragmatic, multicentre, three-arm, randomised, placebo-controlled phase 4 trial
Philpott, C., Beard, D. J., Saeedi, E., Cook, J. A., Jones, S., Clarke, C. S., Teoh, L., Thomas, M., Little, P., Vennik, J., Lund, V., Schilder, A. G. M., Long, F., Durham, S., Boardman, J., Hopkins, C. & on behalf of the MACRO Collaborative, 30 Aug 2025, In: The Lancet. 406, 10506, p. 926-939 14 p.
Research output: Contribution to journal › Article › peer-review

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3 Citations (Scopus)

9 Downloads (Pure)

Cite this

TY - JOUR

T1 - The MACRO Trial: defining best management of chronic rhinosinusitis

AU - Klyvyte, Gabija

AU - Philpott, Carl

AU - Hopkins, Claire

PY - 2026/1/8

Y1 - 2026/1/8

KW - chronic rhinosinusitis

KW - endoscopic sinus surgery

UR - https://www.entandaudiologynews.com/features/ent-features/post/the-macro-trial-defining-best-management-of-chronic-rhinosinusitis

M3 - Review article

JO - ENT News

JF - ENT News

ER -