The pathophysiology of heart failure with preserved ejection fraction: from molecular mechanisms to exercise haemodynamics

Thanh T. Phan, Ganesh Nallur Shivu, Khalid Abozguia, John E. Sanderson, Michael Frenneaux

Research output: Contribution to journalArticlepeer-review

37 Citations (Scopus)


The pathophysiology of HfpEF is complex. In this review we discuss the molecular aspects of HfpEF as well as the profoundly disturbed haemodynamics with particular focus on exercise haemodynamic abnormalities.
Original languageEnglish
Pages (from-to)337-343
Number of pages7
JournalInternational Journal of Cardiology
Issue number3
Publication statusPublished - 26 Jul 2012


  • Exercise
  • Heart Failure
  • Hemodynamics
  • Humans
  • Hypertension
  • Hypertrophy, Left Ventricular
  • Stroke Volume
  • Vascular Stiffness

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