The Pfam protein families database

Alex Bateman; Lachlan Coin; Richard Durbin; Robert D Finn; Volker Hollich; Sam Griffiths-Jones; Ajay Khanna; Mhairi Marshall; Simon Moxon; Erik L L Sonnhammer; David J Studholme; Corin Yeats; Sean R Eddy

doi:10.1093/nar/gkh121

The Pfam protein families database

Alex Bateman, Lachlan Coin, Richard Durbin, Robert D Finn, Volker Hollich, Sam Griffiths-Jones, Ajay Khanna, Mhairi Marshall, Simon Moxon, Erik L L Sonnhammer, David J Studholme, Corin Yeats, Sean R Eddy

School of Biological Sciences

Research output: Contribution to journal › Article › peer-review

3001 Citations (Scopus)

Abstract

Pfam is a large collection of protein families and domains. Over the past 2 years the number of families in Pfam has doubled and now stands at 6190 (version 10.0). Methodology improvements for searching the Pfam collection locally as well as via the web are described. Other recent innovations include modelling of discontinuous domains allowing Pfam domain definitions to be closer to those found in structure databases. Pfam is available on the web in the UK (http://www.sanger.ac.uk/Software/Pfam/), the USA (http://pfam.wustl.edu/), France (http://pfam.jouy.inra.fr/) and Sweden (http://Pfam.cgb.ki.se/).

Original language	English
Pages (from-to)	D138-D141
Number of pages	4
Journal	Nucleic Acids Research
Volume	32
Issue number	Suppl 1
DOIs	https://doi.org/10.1093/nar/gkh121
Publication status	Published - 2004

Access to Document

10.1093/nar/gkh121

Cite this

@article{8195a01852844e8384c7b4e9c227ab71,

title = "The Pfam protein families database",

abstract = "Pfam is a large collection of protein families and domains. Over the past 2 years the number of families in Pfam has doubled and now stands at 6190 (version 10.0). Methodology improvements for searching the Pfam collection locally as well as via the web are described. Other recent innovations include modelling of discontinuous domains allowing Pfam domain definitions to be closer to those found in structure databases. Pfam is available on the web in the UK (http://www.sanger.ac.uk/Software/Pfam/), the USA (http://pfam.wustl.edu/), France (http://pfam.jouy.inra.fr/) and Sweden (http://Pfam.cgb.ki.se/).",

author = "Alex Bateman and Lachlan Coin and Richard Durbin and Finn, {Robert D} and Volker Hollich and Sam Griffiths-Jones and Ajay Khanna and Mhairi Marshall and Simon Moxon and Sonnhammer, {Erik L L} and Studholme, {David J} and Corin Yeats and Eddy, {Sean R}",

year = "2004",

doi = "10.1093/nar/gkh121",

language = "English",

volume = "32",

pages = "D138--D141",

journal = "Nucleic Acids Research",

issn = "0305-1048",

publisher = "Oxford University Press",

number = "Suppl 1",

}

The Pfam protein families database. / Bateman, Alex; Coin, Lachlan; Durbin, Richard; Finn, Robert D; Hollich, Volker; Griffiths-Jones, Sam; Khanna, Ajay; Marshall, Mhairi; Moxon, Simon; Sonnhammer, Erik L L; Studholme, David J; Yeats, Corin; Eddy, Sean R.

In: Nucleic Acids Research, Vol. 32, No. Suppl 1, 2004, p. D138-D141.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - The Pfam protein families database

AU - Bateman, Alex

AU - Coin, Lachlan

AU - Durbin, Richard

AU - Finn, Robert D

AU - Hollich, Volker

AU - Griffiths-Jones, Sam

AU - Khanna, Ajay

AU - Marshall, Mhairi

AU - Moxon, Simon

AU - Sonnhammer, Erik L L

AU - Studholme, David J

AU - Yeats, Corin

AU - Eddy, Sean R

PY - 2004

Y1 - 2004

N2 - Pfam is a large collection of protein families and domains. Over the past 2 years the number of families in Pfam has doubled and now stands at 6190 (version 10.0). Methodology improvements for searching the Pfam collection locally as well as via the web are described. Other recent innovations include modelling of discontinuous domains allowing Pfam domain definitions to be closer to those found in structure databases. Pfam is available on the web in the UK (http://www.sanger.ac.uk/Software/Pfam/), the USA (http://pfam.wustl.edu/), France (http://pfam.jouy.inra.fr/) and Sweden (http://Pfam.cgb.ki.se/).

AB - Pfam is a large collection of protein families and domains. Over the past 2 years the number of families in Pfam has doubled and now stands at 6190 (version 10.0). Methodology improvements for searching the Pfam collection locally as well as via the web are described. Other recent innovations include modelling of discontinuous domains allowing Pfam domain definitions to be closer to those found in structure databases. Pfam is available on the web in the UK (http://www.sanger.ac.uk/Software/Pfam/), the USA (http://pfam.wustl.edu/), France (http://pfam.jouy.inra.fr/) and Sweden (http://Pfam.cgb.ki.se/).

U2 - 10.1093/nar/gkh121

DO - 10.1093/nar/gkh121

M3 - Article

C2 - 14681378

VL - 32

SP - D138-D141

JO - Nucleic Acids Research

JF - Nucleic Acids Research

SN - 0305-1048

IS - Suppl 1

ER -