The Phytochemistry and Pharmacology of Hypericum

Chuan-Yun Xiao, Qing Mu, Simon Gibbons

    Research output: Chapter in Book/Report/Conference proceedingChapter

    12 Citations (Scopus)

    Abstract

    Hypericum L. is a genus of the family Hypericaceae within the dicotyledones. The constituents of Hypericum species are valued for their important biological properties. Their use is in the treatment of depression and as antibacterial agents has been well documented in the primary literature and in ethnobotanical reports. The present contribution gives a comprehensive summary of the chemical constituents of members of the genus Hypericum and their biological effects. A detailed account of the chemical constituents, including phloroglucinol derivatives, xanthones, dianthrones, and flavonoids, is included. These compounds show a diverse range of biological activities that include antimicrobial, cytotoxic, antidepressant-like, and antinociceptive effects.

    Original languageEnglish
    Title of host publication Progress in the Chemistry of Organic Natural Products
    EditorsA. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Jun'ichi Kobayashi, Yoshinori Asakawa, Ji-Kai Liu
    Chapter2
    Pages85-182
    Number of pages98
    ISBN (Electronic)978-3-030-52966-6
    DOIs
    Publication statusPublished - 12 Dec 2020

    Publication series

    NameProgress in the Chemistry of Organic Natural Products 112
    Volume112
    ISSN (Print)2191-7043
    ISSN (Electronic)2192-4309

    Keywords

    • Biological activities
    • Chemical constituents
    • Hypericum

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