The potential role of the mobile and non-coding genomes in adaptive response

Alice M. Godden; Simone Immler

doi:10.1016/j.tig.2022.08.006

The potential role of the mobile and non-coding genomes in adaptive response

Alice M. Godden, Simone Immler

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

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Abstract

The tightly regulated feedback loops linking small RNAs (sRNAs) and transposable elements (TEs) offer the opportunity for an adaptive response to changing environments at the molecular level. Environmentally induced changes in TE and sRNA profiles may affect expression of coding genes and trigger an organismic and transgenerational response. Understanding this link may provide a mechanistic explanation for how species can adapt to changing climates and may offer novel molecular targets for biomedical and agricultural applications.

Original language	English
Pages (from-to)	5-8
Number of pages	4
Journal	Trends in Genetics
Volume	39
Issue number	1
Early online date	1 Sep 2022
DOIs	https://doi.org/10.1016/j.tig.2022.08.006
Publication status	Published - Jan 2023

Keywords

epigenetic
germ cells
miRNAs
piRNAs
transposable elements

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10.1016/j.tig.2022.08.006Licence: CC BY

Godden_Immler_2022_TiGProof, 625 KBLicence: CC BY

Cite this

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abstract = "The tightly regulated feedback loops linking small RNAs (sRNAs) and transposable elements (TEs) offer the opportunity for an adaptive response to changing environments at the molecular level. Environmentally induced changes in TE and sRNA profiles may affect expression of coding genes and trigger an organismic and transgenerational response. Understanding this link may provide a mechanistic explanation for how species can adapt to changing climates and may offer novel molecular targets for biomedical and agricultural applications.",

keywords = "epigenetic, germ cells, miRNAs, piRNAs, transposable elements",

author = "Godden, {Alice M.} and Simone Immler",

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N2 - The tightly regulated feedback loops linking small RNAs (sRNAs) and transposable elements (TEs) offer the opportunity for an adaptive response to changing environments at the molecular level. Environmentally induced changes in TE and sRNA profiles may affect expression of coding genes and trigger an organismic and transgenerational response. Understanding this link may provide a mechanistic explanation for how species can adapt to changing climates and may offer novel molecular targets for biomedical and agricultural applications.

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KW - piRNAs

KW - transposable elements

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The potential role of the mobile and non-coding genomes in adaptive response

Abstract

Keywords

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Other files and links

Understanding the role of selection at the gametic level in adaptation to changing environments

Haploid selection in animals: investigating the importance of genetic and epigenetic effects in sperm

Cite this

The potential role of the mobile and non-coding genomes in adaptive response

Abstract

Keywords

Access to Document

Other files and links

Projects

Understanding the role of selection at the gametic level in adaptation to changing environments

Haploid selection in animals: investigating the importance of genetic and epigenetic effects in sperm

Cite this