Abstract
Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used agents that can cause serious gastrointestinal (GI) side effects. For patients at increased risk of NSAID-related GI complications, prophylaxis with either a nonselective NSAID plus gastroprotective agent (GPA) or, alternatively, therapy with a cyclooxygenase-2 selective inhibitor with or without a GPA such as a proton pump inhibitor (PPI), is recommended.
Original language | English |
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Pages (from-to) | 481-488 |
Number of pages | 8 |
Journal | Canadian Journal of Gastroenterology |
Volume | 24 |
Issue number | 8 |
Publication status | Published - Aug 2010 |
Keywords
- Aged
- Aged, 80 and over
- Anti-Inflammatory Agents, Non-Steroidal
- Cyclooxygenase 2 Inhibitors
- Female
- Gastrointestinal Diseases
- Gastrointestinal Tract
- Histamine H2 Antagonists
- Humans
- Male
- Nova Scotia
- Proton Pump Inhibitors
- Retrospective Studies
- Risk Factors