The rate of prescribing gastrointestinal prophylaxis with either a proton pump inhibitor or an H2-receptor antagonist in Nova Scotia seniors starting nonsteroidal anti-inflammatory drug therapy

Bogdan Superceanu, Sander Veldhuyzen van Zanten, Chris Skedgel, Michael Shepherd, Ingrid Sketris

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used agents that can cause serious gastrointestinal (GI) side effects. For patients at increased risk of NSAID-related GI complications, prophylaxis with either a nonselective NSAID plus gastroprotective agent (GPA) or, alternatively, therapy with a cyclooxygenase-2 selective inhibitor with or without a GPA such as a proton pump inhibitor (PPI), is recommended.
Original languageEnglish
Pages (from-to)481-488
Number of pages8
JournalCanadian Journal of Gastroenterology
Volume24
Issue number8
Publication statusPublished - Aug 2010

Keywords

  • Aged
  • Aged, 80 and over
  • Anti-Inflammatory Agents, Non-Steroidal
  • Cyclooxygenase 2 Inhibitors
  • Female
  • Gastrointestinal Diseases
  • Gastrointestinal Tract
  • Histamine H2 Antagonists
  • Humans
  • Male
  • Nova Scotia
  • Proton Pump Inhibitors
  • Retrospective Studies
  • Risk Factors

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