The role of late gadolinium enhancement in predicting arrhythmic events in cardiac sarcoidosis patients – A mini-review

George Bazoukis; Ioannis Liatakis; Vassilios S. Vassiliou; Gary Tse; Pantelis Gounopoulos; Athanasios Saplaouras; Konstantinos P. Letsas; Konstantinos Vlachos; Stamatis S. Papadatos; Eleni Konstantinidou; Ioannis Lakoumentas; Antonios Sideris; Michael Efremidis

doi:10.1080/00015385.2022.2029231

The role of late gadolinium enhancement in predicting arrhythmic events in cardiac sarcoidosis patients – A mini-review

George Bazoukis, Ioannis Liatakis, Vassilios S. Vassiliou, Gary Tse, Pantelis Gounopoulos, Athanasios Saplaouras, Konstantinos P. Letsas, Konstantinos Vlachos, Stamatis S. Papadatos, Eleni Konstantinidou, Ioannis Lakoumentas, Antonios Sideris, Michael Efremidis

Research output: Contribution to journal › Review article › peer-review

1 Citation (Scopus)

5 Downloads (Pure)

Abstract

Sarcoidosis is a multisystem inflammatory disorder with an unknown origin. Symptomatic cardiac involvement is rare and occurs in about 5% of patients with sarcoidosis. Fatal ventricular arrhythmias are the most severe clinical presentation of the disease. Cardiac magnetic resonance (CMR) is a useful non-invasive tool for the risk stratification of ventricular arrhythmias and sudden cardiac death (SCD) in patients with cardiac sarcoidosis (CS). More specifically, late gadolinium enhancement (LGE), a CMR tool for scar detection, has been found to be significantly associated with arrhythmic events in CS patients. This review aims to present the existing evidence regarding the association of LGE with adverse events and especially with fatal ventricular arrhythmias.

Original language	English
Pages (from-to)	768-773
Number of pages	6
Journal	Acta Cardiologica
Volume	77
Issue number	9
Early online date	28 Jan 2022
DOIs	https://doi.org/10.1080/00015385.2022.2029231
Publication status	Published - Dec 2022

Keywords

Cardiac magnetic resonance
cardiac sarcoidosis
late gadolinium enhancement
sudden cardiac death
ventricular arrhythmias

Access to Document

10.1080/00015385.2022.2029231

Accepted_MnauscriptAccepted author manuscript, 249 KBLicence: CC BY-NC

Cite this

Bazoukis, G., Liatakis, I., Vassiliou, V. S., Tse, G., Gounopoulos, P., Saplaouras, A., Letsas, K. P., Vlachos, K., Papadatos, S. S., Konstantinidou, E., Lakoumentas, I., Sideris, A., & Efremidis, M. (2022). The role of late gadolinium enhancement in predicting arrhythmic events in cardiac sarcoidosis patients – A mini-review. Acta Cardiologica, 77(9), 768-773. https://doi.org/10.1080/00015385.2022.2029231

Bazoukis, George ; Liatakis, Ioannis ; Vassiliou, Vassilios S. ; Tse, Gary ; Gounopoulos, Pantelis ; Saplaouras, Athanasios ; Letsas, Konstantinos P. ; Vlachos, Konstantinos ; Papadatos, Stamatis S. ; Konstantinidou, Eleni ; Lakoumentas, Ioannis ; Sideris, Antonios ; Efremidis, Michael. / The role of late gadolinium enhancement in predicting arrhythmic events in cardiac sarcoidosis patients – A mini-review. In: Acta Cardiologica. 2022 ; Vol. 77, No. 9. pp. 768-773.

@article{1629f1205b404cf8a8d82dc578e137b0,

title = "The role of late gadolinium enhancement in predicting arrhythmic events in cardiac sarcoidosis patients – A mini-review",

abstract = "Sarcoidosis is a multisystem inflammatory disorder with an unknown origin. Symptomatic cardiac involvement is rare and occurs in about 5% of patients with sarcoidosis. Fatal ventricular arrhythmias are the most severe clinical presentation of the disease. Cardiac magnetic resonance (CMR) is a useful non-invasive tool for the risk stratification of ventricular arrhythmias and sudden cardiac death (SCD) in patients with cardiac sarcoidosis (CS). More specifically, late gadolinium enhancement (LGE), a CMR tool for scar detection, has been found to be significantly associated with arrhythmic events in CS patients. This review aims to present the existing evidence regarding the association of LGE with adverse events and especially with fatal ventricular arrhythmias.",

keywords = "Cardiac magnetic resonance, cardiac sarcoidosis, late gadolinium enhancement, sudden cardiac death, ventricular arrhythmias",

author = "George Bazoukis and Ioannis Liatakis and Vassiliou, {Vassilios S.} and Gary Tse and Pantelis Gounopoulos and Athanasios Saplaouras and Letsas, {Konstantinos P.} and Konstantinos Vlachos and Papadatos, {Stamatis S.} and Eleni Konstantinidou and Ioannis Lakoumentas and Antonios Sideris and Michael Efremidis",

year = "2022",

month = dec,

doi = "10.1080/00015385.2022.2029231",

language = "English",

volume = "77",

pages = "768--773",

journal = "Acta Cardiologica",

issn = "0001-5385",

publisher = "Taylor and Francis",

number = "9",

}

Bazoukis, G, Liatakis, I, Vassiliou, VS, Tse, G, Gounopoulos, P, Saplaouras, A, Letsas, KP, Vlachos, K, Papadatos, SS, Konstantinidou, E, Lakoumentas, I, Sideris, A & Efremidis, M 2022, 'The role of late gadolinium enhancement in predicting arrhythmic events in cardiac sarcoidosis patients – A mini-review', Acta Cardiologica, vol. 77, no. 9, pp. 768-773. https://doi.org/10.1080/00015385.2022.2029231

The role of late gadolinium enhancement in predicting arrhythmic events in cardiac sarcoidosis patients – A mini-review. / Bazoukis, George; Liatakis, Ioannis; Vassiliou, Vassilios S.; Tse, Gary; Gounopoulos, Pantelis; Saplaouras, Athanasios; Letsas, Konstantinos P.; Vlachos, Konstantinos; Papadatos, Stamatis S.; Konstantinidou, Eleni; Lakoumentas, Ioannis; Sideris, Antonios; Efremidis, Michael.

In: Acta Cardiologica, Vol. 77, No. 9, 12.2022, p. 768-773.

Research output: Contribution to journal › Review article › peer-review

TY - JOUR

T1 - The role of late gadolinium enhancement in predicting arrhythmic events in cardiac sarcoidosis patients – A mini-review

AU - Bazoukis, George

AU - Liatakis, Ioannis

AU - Vassiliou, Vassilios S.

AU - Tse, Gary

AU - Gounopoulos, Pantelis

AU - Saplaouras, Athanasios

AU - Letsas, Konstantinos P.

AU - Vlachos, Konstantinos

AU - Papadatos, Stamatis S.

AU - Konstantinidou, Eleni

AU - Lakoumentas, Ioannis

AU - Sideris, Antonios

AU - Efremidis, Michael

PY - 2022/12

Y1 - 2022/12

N2 - Sarcoidosis is a multisystem inflammatory disorder with an unknown origin. Symptomatic cardiac involvement is rare and occurs in about 5% of patients with sarcoidosis. Fatal ventricular arrhythmias are the most severe clinical presentation of the disease. Cardiac magnetic resonance (CMR) is a useful non-invasive tool for the risk stratification of ventricular arrhythmias and sudden cardiac death (SCD) in patients with cardiac sarcoidosis (CS). More specifically, late gadolinium enhancement (LGE), a CMR tool for scar detection, has been found to be significantly associated with arrhythmic events in CS patients. This review aims to present the existing evidence regarding the association of LGE with adverse events and especially with fatal ventricular arrhythmias.

AB - Sarcoidosis is a multisystem inflammatory disorder with an unknown origin. Symptomatic cardiac involvement is rare and occurs in about 5% of patients with sarcoidosis. Fatal ventricular arrhythmias are the most severe clinical presentation of the disease. Cardiac magnetic resonance (CMR) is a useful non-invasive tool for the risk stratification of ventricular arrhythmias and sudden cardiac death (SCD) in patients with cardiac sarcoidosis (CS). More specifically, late gadolinium enhancement (LGE), a CMR tool for scar detection, has been found to be significantly associated with arrhythmic events in CS patients. This review aims to present the existing evidence regarding the association of LGE with adverse events and especially with fatal ventricular arrhythmias.

KW - Cardiac magnetic resonance

KW - cardiac sarcoidosis

KW - late gadolinium enhancement

KW - sudden cardiac death

KW - ventricular arrhythmias

UR - http://www.scopus.com/inward/record.url?scp=85124171117&partnerID=8YFLogxK

U2 - 10.1080/00015385.2022.2029231

DO - 10.1080/00015385.2022.2029231

M3 - Review article

VL - 77

SP - 768

EP - 773

JO - Acta Cardiologica

JF - Acta Cardiologica

SN - 0001-5385

IS - 9

ER -

The role of late gadolinium enhancement in predicting arrhythmic events in cardiac sarcoidosis patients – A mini-review

Abstract

Keywords

Access to Document

Other files and links

Cite this