The secondary metabolites of aff. Samadera SAC-2825: An Australian simaroubaceae with unusual chemistry

Simon Gibbons; Lyn Craven; Clyde Dunlop; Alexander I. Gray; Thomas G. Hartley; Peter G. Waterman

doi:10.1016/S0031-9422(96)00708-X

The secondary metabolites of aff. Samadera SAC-2825: An Australian simaroubaceae with unusual chemistry

Simon Gibbons, Lyn Craven, Clyde Dunlop, Alexander I. Gray, Thomas G. Hartley, Peter G. Waterman

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

The phytochemical analysis of two collections of a new species (SAC-2825), tentatively assigned as aff. Samadera bidwillii (Simaroubaceae), has yielded a limonoid (limonin), a quassinoid (2′-acetoxyglaucarubin), three alkaloids [2-(10′ξ-acetoxyundecanyl)-1-acetoxymethyl-4-quinolone, 1-methoxy-10-methyl-acridan-9-one and 1,8-dihydroxyacridan-9-one] and seven bicyclo-octane type lignans [(−)-sesamin, (−)-episesamin, fargesin, neofargesin, (−)-kobusin, (−)-epieudesmin and (−)-eudesmin]. The 4-quinolone alkaloid appears to be novel. The metabolites identified are collectively typical of the Rutales, but have a biosynthetic range never previously found together in a single species. Particularly noteworthy is the co-occurrence of limonoids and quassinoids in the same plant, which is currently unique to SAC-2825.

Original language	English
Pages (from-to)	1109-1114
Number of pages	6
Journal	Phytochemistry
Volume	44
Issue number	6
DOIs	https://doi.org/10.1016/S0031-9422(96)00708-X
Publication status	Published - 1 Mar 1997

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10.1016/S0031-9422(96)00708-X

https://linkinghub.elsevier.com/retrieve/pii/S003194229600708X

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@article{de1ee34934f74e518a83a5625b3366be,

title = "The secondary metabolites of aff. Samadera SAC-2825: An Australian simaroubaceae with unusual chemistry",

abstract = "The phytochemical analysis of two collections of a new species (SAC-2825), tentatively assigned as aff. Samadera bidwillii (Simaroubaceae), has yielded a limonoid (limonin), a quassinoid (2′-acetoxyglaucarubin), three alkaloids [2-(10′ξ-acetoxyundecanyl)-1-acetoxymethyl-4-quinolone, 1-methoxy-10-methyl-acridan-9-one and 1,8-dihydroxyacridan-9-one] and seven bicyclo-octane type lignans [(−)-sesamin, (−)-episesamin, fargesin, neofargesin, (−)-kobusin, (−)-epieudesmin and (−)-eudesmin]. The 4-quinolone alkaloid appears to be novel. The metabolites identified are collectively typical of the Rutales, but have a biosynthetic range never previously found together in a single species. Particularly noteworthy is the co-occurrence of limonoids and quassinoids in the same plant, which is currently unique to SAC-2825.",

author = "Simon Gibbons and Lyn Craven and Clyde Dunlop and Gray, {Alexander I.} and Hartley, {Thomas G.} and Waterman, {Peter G.}",

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T1 - The secondary metabolites of aff. Samadera SAC-2825: An Australian simaroubaceae with unusual chemistry

AU - Gibbons, Simon

AU - Craven, Lyn

AU - Dunlop, Clyde

AU - Gray, Alexander I.

AU - Hartley, Thomas G.

AU - Waterman, Peter G.

PY - 1997/3/1

Y1 - 1997/3/1

N2 - The phytochemical analysis of two collections of a new species (SAC-2825), tentatively assigned as aff. Samadera bidwillii (Simaroubaceae), has yielded a limonoid (limonin), a quassinoid (2′-acetoxyglaucarubin), three alkaloids [2-(10′ξ-acetoxyundecanyl)-1-acetoxymethyl-4-quinolone, 1-methoxy-10-methyl-acridan-9-one and 1,8-dihydroxyacridan-9-one] and seven bicyclo-octane type lignans [(−)-sesamin, (−)-episesamin, fargesin, neofargesin, (−)-kobusin, (−)-epieudesmin and (−)-eudesmin]. The 4-quinolone alkaloid appears to be novel. The metabolites identified are collectively typical of the Rutales, but have a biosynthetic range never previously found together in a single species. Particularly noteworthy is the co-occurrence of limonoids and quassinoids in the same plant, which is currently unique to SAC-2825.

AB - The phytochemical analysis of two collections of a new species (SAC-2825), tentatively assigned as aff. Samadera bidwillii (Simaroubaceae), has yielded a limonoid (limonin), a quassinoid (2′-acetoxyglaucarubin), three alkaloids [2-(10′ξ-acetoxyundecanyl)-1-acetoxymethyl-4-quinolone, 1-methoxy-10-methyl-acridan-9-one and 1,8-dihydroxyacridan-9-one] and seven bicyclo-octane type lignans [(−)-sesamin, (−)-episesamin, fargesin, neofargesin, (−)-kobusin, (−)-epieudesmin and (−)-eudesmin]. The 4-quinolone alkaloid appears to be novel. The metabolites identified are collectively typical of the Rutales, but have a biosynthetic range never previously found together in a single species. Particularly noteworthy is the co-occurrence of limonoids and quassinoids in the same plant, which is currently unique to SAC-2825.

U2 - 10.1016/S0031-9422(96)00708-X

DO - 10.1016/S0031-9422(96)00708-X

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VL - 44

SP - 1109

EP - 1114

JO - Phytochemistry

JF - Phytochemistry

SN - 0031-9422

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