The shoot apical meristem regulatory peptide CLV3 does not activate innate immunity

Cécile Segonzac; Zachary L Nimchuk; Martina Beck; Paul T Tarr; Silke Robatzek; Elliot M Meyerowitz; Cyril Zipfel

doi:10.1105/tpc.111.091264

The shoot apical meristem regulatory peptide CLV3 does not activate innate immunity

Cécile Segonzac, Zachary L Nimchuk, Martina Beck, Paul T Tarr, Silke Robatzek, Elliot M Meyerowitz, Cyril Zipfel

Research output: Contribution to journal › Article › peer-review

27 Citations (Scopus)

Abstract

The Arabidopsis thaliana leucine-rich repeat receptor kinase FLAGELLIN SENSING2 (FLS2) is required for the recognition of bacterial flagellin in innate immunity. Recently, FLS2 was proposed to act as a multispecific receptor recognizing unrelated exogenous and endogenous peptide ligands, including CLAVATA3 (CLV3), a key regulator of shoot meristem stem cell production. Here, we report experimental evidence demonstrating that FLS2 does not recognize CLV3 and that the shoot apical meristem is immune to bacteria independently of CLV3 perception.

Original language	English
Pages (from-to)	3186-3192
Number of pages	7
Journal	The Plant Cell
Volume	24
Issue number	8
DOIs	https://doi.org/10.1105/tpc.111.091264
Publication status	Published - Aug 2012

Keywords

Arabidopsis
Arabidopsis Proteins
Enzyme Activation
Green Fluorescent Proteins
Host-Pathogen Interactions
Ligands
Meristem
Plant Diseases
Plant Immunity
Plant Shoots
Plants, Genetically Modified
Protein Binding
Protein Kinases
Pseudomonas syringae
Receptors, Cell Surface

Access to Document

10.1105/tpc.111.091264

Cite this

@article{760b0d6161614158bdc1a556f9e3aaca,

title = "The shoot apical meristem regulatory peptide CLV3 does not activate innate immunity",

abstract = "The Arabidopsis thaliana leucine-rich repeat receptor kinase FLAGELLIN SENSING2 (FLS2) is required for the recognition of bacterial flagellin in innate immunity. Recently, FLS2 was proposed to act as a multispecific receptor recognizing unrelated exogenous and endogenous peptide ligands, including CLAVATA3 (CLV3), a key regulator of shoot meristem stem cell production. Here, we report experimental evidence demonstrating that FLS2 does not recognize CLV3 and that the shoot apical meristem is immune to bacteria independently of CLV3 perception.",

keywords = "Arabidopsis, Arabidopsis Proteins, Enzyme Activation, Green Fluorescent Proteins, Host-Pathogen Interactions, Ligands, Meristem, Plant Diseases, Plant Immunity, Plant Shoots, Plants, Genetically Modified, Protein Binding, Protein Kinases, Pseudomonas syringae, Receptors, Cell Surface",

author = "C{\'e}cile Segonzac and Nimchuk, {Zachary L} and Martina Beck and Tarr, {Paul T} and Silke Robatzek and Meyerowitz, {Elliot M} and Cyril Zipfel",

year = "2012",

month = aug,

doi = "10.1105/tpc.111.091264",

language = "English",

volume = "24",

pages = "3186--3192",

journal = "The Plant Cell",

issn = "1040-4651",

publisher = "American Society of Plant Biologists",

number = "8",

}

TY - JOUR

T1 - The shoot apical meristem regulatory peptide CLV3 does not activate innate immunity

AU - Segonzac, Cécile

AU - Nimchuk, Zachary L

AU - Beck, Martina

AU - Tarr, Paul T

AU - Robatzek, Silke

AU - Meyerowitz, Elliot M

AU - Zipfel, Cyril

PY - 2012/8

Y1 - 2012/8

N2 - The Arabidopsis thaliana leucine-rich repeat receptor kinase FLAGELLIN SENSING2 (FLS2) is required for the recognition of bacterial flagellin in innate immunity. Recently, FLS2 was proposed to act as a multispecific receptor recognizing unrelated exogenous and endogenous peptide ligands, including CLAVATA3 (CLV3), a key regulator of shoot meristem stem cell production. Here, we report experimental evidence demonstrating that FLS2 does not recognize CLV3 and that the shoot apical meristem is immune to bacteria independently of CLV3 perception.

AB - The Arabidopsis thaliana leucine-rich repeat receptor kinase FLAGELLIN SENSING2 (FLS2) is required for the recognition of bacterial flagellin in innate immunity. Recently, FLS2 was proposed to act as a multispecific receptor recognizing unrelated exogenous and endogenous peptide ligands, including CLAVATA3 (CLV3), a key regulator of shoot meristem stem cell production. Here, we report experimental evidence demonstrating that FLS2 does not recognize CLV3 and that the shoot apical meristem is immune to bacteria independently of CLV3 perception.

KW - Arabidopsis

KW - Arabidopsis Proteins

KW - Enzyme Activation

KW - Green Fluorescent Proteins

KW - Host-Pathogen Interactions

KW - Ligands

KW - Meristem

KW - Plant Diseases

KW - Plant Immunity

KW - Plant Shoots

KW - Plants, Genetically Modified

KW - Protein Binding

KW - Protein Kinases

KW - Pseudomonas syringae

KW - Receptors, Cell Surface

U2 - 10.1105/tpc.111.091264

DO - 10.1105/tpc.111.091264

M3 - Article

C2 - 22923673

VL - 24

SP - 3186

EP - 3192

JO - The Plant Cell

JF - The Plant Cell

SN - 1040-4651

IS - 8

ER -