Abstract
Background: The epidemiology of first episodepsychoses [FEP] is predominantly based on observational research from urban populations. It is unclear whether findings extend to more rural communities, particularly with regard to risk by place and ethnicity.
Methods: All people, 16-35 years, referred to 6 early intervention in psychosis services [EIS] with suspected FEP over 3.5 years were identified in East Anglia.
Participants were excluded if they had: previous contact with mental health services for psychosis; insufficient symptoms for EIS
acceptance; residence outside the catchment, or; an organic basis to disorder. ICD-10 operationalised diagnoses (F10-33) were ascertained six months after EIS acceptance.
Sociodemographic data were collected using a standardised schedule. Corresponding denominator data were estimated from the 2011 census. Poisson regression was used to analyse incidence.
Results: 673 people with FEP were identified 33.3/100,000 person-years; 95%CI: 30.9-35.9). Median age-at-referral was around 22.5 years for men and women, although incidence was higher in men (incidence rate ratio [IRR]: 1.95; 95%CI: 1.64- 2.31), after adjustment for age, ethnicity and EIS.
Rates were raised for several ethnic minority groups, including the black Caribbean, black African, Pakistani, Bangladeshi and Arabic groups, after control for confounding. Rates also varied by neighbourhood-level exposures, including deprivation (IRR: 1.015; 95%CI: 1.003-1.026), ethnic cohesion (IRR: 0.988; 95%CI: 0.977-0.999), proportion of single-person households (IRR: 1.029; 95%CI: 1.015-1.044) and proportion of 16-35 year olds (IRR: 0.988; 95%CI: 0.978-0.997).
Conclusions: FEP incidence varies by ethnicity and place in rural communities in similar ways to more urban populations, with markers of
neighbourhood-level social support and socioeconomic deprivation predictiveof incidence.
Methods: All people, 16-35 years, referred to 6 early intervention in psychosis services [EIS] with suspected FEP over 3.5 years were identified in East Anglia.
Participants were excluded if they had: previous contact with mental health services for psychosis; insufficient symptoms for EIS
acceptance; residence outside the catchment, or; an organic basis to disorder. ICD-10 operationalised diagnoses (F10-33) were ascertained six months after EIS acceptance.
Sociodemographic data were collected using a standardised schedule. Corresponding denominator data were estimated from the 2011 census. Poisson regression was used to analyse incidence.
Results: 673 people with FEP were identified 33.3/100,000 person-years; 95%CI: 30.9-35.9). Median age-at-referral was around 22.5 years for men and women, although incidence was higher in men (incidence rate ratio [IRR]: 1.95; 95%CI: 1.64- 2.31), after adjustment for age, ethnicity and EIS.
Rates were raised for several ethnic minority groups, including the black Caribbean, black African, Pakistani, Bangladeshi and Arabic groups, after control for confounding. Rates also varied by neighbourhood-level exposures, including deprivation (IRR: 1.015; 95%CI: 1.003-1.026), ethnic cohesion (IRR: 0.988; 95%CI: 0.977-0.999), proportion of single-person households (IRR: 1.029; 95%CI: 1.015-1.044) and proportion of 16-35 year olds (IRR: 0.988; 95%CI: 0.978-0.997).
Conclusions: FEP incidence varies by ethnicity and place in rural communities in similar ways to more urban populations, with markers of
neighbourhood-level social support and socioeconomic deprivation predictiveof incidence.
| Original language | English |
|---|---|
| Publication status | Published - 2014 |
| Event | MHN National Scietific Meeting - Liverpool, United Kingdom Duration: 5 Mar 2014 → 7 Mar 2014 |
Conference
| Conference | MHN National Scietific Meeting |
|---|---|
| Country/Territory | United Kingdom |
| City | Liverpool |
| Period | 5/03/14 → 7/03/14 |
