The structure of procalcitonin of the salmon as deduced from its cDNA sequence

E Pöschl; I Lindley; E Hofer; J M Seifert; W Brunowsky; J Besemer

doi:10.1016/0014-5793(87)80558-6

The structure of procalcitonin of the salmon as deduced from its cDNA sequence

E Pöschl, I Lindley, E Hofer, J M Seifert, W Brunowsky, J Besemer

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

Oligonucleotide probes based on the known amino acid sequence of salmon calcitonin were used to screen a cDNA library obtained from ultimobranchial glands of salmon for clones encoding salmon calcitonin. From the cDNA sequence of strongly hybridizing clones the complete primary structure of the calcitonin precursor could be deduced. Its overall structure is identical with the structures of procalcitonins from other vertebrates and has the highest homology with the chicken precursor.

Original language	English
Pages (from-to)	96-100
Number of pages	5
Journal	FEBS Letters
Volume	226
Issue number	1
DOIs	https://doi.org/10.1016/0014-5793(87)80558-6
Publication status	Published - 21 Dec 1987

Keywords

Amino Acid Sequence
Animals
Base Sequence
Calcitonin
DNA
Glycoproteins
Molecular Sequence Data
Nucleic Acid Hybridization
Protein Precursors
Salmon

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10.1016/0014-5793(87)80558-6

Cite this

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title = "The structure of procalcitonin of the salmon as deduced from its cDNA sequence",

abstract = "Oligonucleotide probes based on the known amino acid sequence of salmon calcitonin were used to screen a cDNA library obtained from ultimobranchial glands of salmon for clones encoding salmon calcitonin. From the cDNA sequence of strongly hybridizing clones the complete primary structure of the calcitonin precursor could be deduced. Its overall structure is identical with the structures of procalcitonins from other vertebrates and has the highest homology with the chicken precursor.",

keywords = "Amino Acid Sequence, Animals, Base Sequence, Calcitonin, DNA, Glycoproteins, Molecular Sequence Data, Nucleic Acid Hybridization, Protein Precursors, Salmon",

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year = "1987",

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T1 - The structure of procalcitonin of the salmon as deduced from its cDNA sequence

AU - Pöschl, E

AU - Lindley, I

AU - Hofer, E

AU - Seifert, J M

AU - Brunowsky, W

AU - Besemer, J

PY - 1987/12/21

Y1 - 1987/12/21

N2 - Oligonucleotide probes based on the known amino acid sequence of salmon calcitonin were used to screen a cDNA library obtained from ultimobranchial glands of salmon for clones encoding salmon calcitonin. From the cDNA sequence of strongly hybridizing clones the complete primary structure of the calcitonin precursor could be deduced. Its overall structure is identical with the structures of procalcitonins from other vertebrates and has the highest homology with the chicken precursor.

AB - Oligonucleotide probes based on the known amino acid sequence of salmon calcitonin were used to screen a cDNA library obtained from ultimobranchial glands of salmon for clones encoding salmon calcitonin. From the cDNA sequence of strongly hybridizing clones the complete primary structure of the calcitonin precursor could be deduced. Its overall structure is identical with the structures of procalcitonins from other vertebrates and has the highest homology with the chicken precursor.

KW - Amino Acid Sequence

KW - Animals

KW - Base Sequence

KW - Calcitonin

KW - DNA

KW - Glycoproteins

KW - Molecular Sequence Data

KW - Nucleic Acid Hybridization

KW - Protein Precursors

KW - Salmon

U2 - 10.1016/0014-5793(87)80558-6

DO - 10.1016/0014-5793(87)80558-6

M3 - Article

C2 - 3691820

VL - 226

SP - 96

EP - 100

JO - FEBS Letters

JF - FEBS Letters

SN - 0014-5793

IS - 1

ER -