The transcriptional regulator BZR1 mediates trade-off between plant innate immunity and growth

Rosa Lozano-Durán; Alberto P Macho; Freddy Boutrot; Cécile Segonzac; Imre E Somssich; Cyril Zipfel

doi:10.7554/eLife.00983

The transcriptional regulator BZR1 mediates trade-off between plant innate immunity and growth

Rosa Lozano-Durán, Alberto P Macho, Freddy Boutrot, Cécile Segonzac, Imre E Somssich, Cyril Zipfel

Research output: Contribution to journal › Article › peer-review

170 Citations (SciVal)

Abstract

The molecular mechanisms underlying the trade-off between plant innate immunity and steroid-mediated growth are controversial. Here, we report that activation of the transcription factor BZR1 is required and sufficient for suppression of immune signaling by brassinosteroids (BR). BZR1 induces the expression of several WRKY transcription factors that negatively control early immune responses. In addition, BZR1 associates with WRKY40 to mediate the antagonism between BR and immune signaling. We reveal that BZR1-mediated inhibition of immunity is particularly relevant when plant fast growth is required, such as during etiolation. Thus, BZR1 acts as an important regulator mediating the trade-off between growth and immunity upon integration of environmental cues. DOI: http://dx.doi.org/10.7554/eLife.00983.001.

Original language	English
Article number	e00983
Journal	eLife
Volume	2
DOIs	https://doi.org/10.7554/eLife.00983
Publication status	Published - 31 Dec 2013

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10.7554/eLife.00983Licence: CC BY

Signaling to plant immunity responses (PathoNet)
Zipfel, C.
Biotechnology and Biological Sciences Research Council
1/10/09 → 30/09/12
Project: Research
Pattern recognition receptors: discovery, function and application in crops for durable disease control
Zipfel, C., Brunner, F., Gust, A., Pugin, A., Ridout, C., Weyen, J. & de Wit, J. G. M.
Biotechnology and Biological Sciences Research Council
1/06/09 → 31/08/12
Project: Research

Cite this

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title = "The transcriptional regulator BZR1 mediates trade-off between plant innate immunity and growth",

abstract = "The molecular mechanisms underlying the trade-off between plant innate immunity and steroid-mediated growth are controversial. Here, we report that activation of the transcription factor BZR1 is required and sufficient for suppression of immune signaling by brassinosteroids (BR). BZR1 induces the expression of several WRKY transcription factors that negatively control early immune responses. In addition, BZR1 associates with WRKY40 to mediate the antagonism between BR and immune signaling. We reveal that BZR1-mediated inhibition of immunity is particularly relevant when plant fast growth is required, such as during etiolation. Thus, BZR1 acts as an important regulator mediating the trade-off between growth and immunity upon integration of environmental cues. DOI: http://dx.doi.org/10.7554/eLife.00983.001.",

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AU - Lozano-Durán, Rosa

AU - Macho, Alberto P

AU - Boutrot, Freddy

AU - Segonzac, Cécile

AU - Somssich, Imre E

AU - Zipfel, Cyril

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PY - 2013/12/31

Y1 - 2013/12/31

N2 - The molecular mechanisms underlying the trade-off between plant innate immunity and steroid-mediated growth are controversial. Here, we report that activation of the transcription factor BZR1 is required and sufficient for suppression of immune signaling by brassinosteroids (BR). BZR1 induces the expression of several WRKY transcription factors that negatively control early immune responses. In addition, BZR1 associates with WRKY40 to mediate the antagonism between BR and immune signaling. We reveal that BZR1-mediated inhibition of immunity is particularly relevant when plant fast growth is required, such as during etiolation. Thus, BZR1 acts as an important regulator mediating the trade-off between growth and immunity upon integration of environmental cues. DOI: http://dx.doi.org/10.7554/eLife.00983.001.

AB - The molecular mechanisms underlying the trade-off between plant innate immunity and steroid-mediated growth are controversial. Here, we report that activation of the transcription factor BZR1 is required and sufficient for suppression of immune signaling by brassinosteroids (BR). BZR1 induces the expression of several WRKY transcription factors that negatively control early immune responses. In addition, BZR1 associates with WRKY40 to mediate the antagonism between BR and immune signaling. We reveal that BZR1-mediated inhibition of immunity is particularly relevant when plant fast growth is required, such as during etiolation. Thus, BZR1 acts as an important regulator mediating the trade-off between growth and immunity upon integration of environmental cues. DOI: http://dx.doi.org/10.7554/eLife.00983.001.

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The transcriptional regulator BZR1 mediates trade-off between plant innate immunity and growth

Abstract

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Projects

Signaling to plant immunity responses (PathoNet)

Pattern recognition receptors: discovery, function and application in crops for durable disease control

Cite this