The utility of a CHA2DS2-VASc score in predicting the presence of significant stenosis and occlusion of veins with indwelling endocardial leads

Krzysztof Boczar, Andrzej Zabek, Maciej Debski, Kazimierz Haberka, Anna Rydlewska, Jacek Lelakowski, Barbara Malecka

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Background: Currently, there are no studies in which a CHA2DS2-VASc score has been used to predict the risk of venous stenosis and occlusion (VSO) in patients after the implantation of a cardiac implantable electronic device (CIED).

Methods: The material consists of the records of 223 consecutive patients qualified for transvenous lead extraction, generator change and system revisions or upgrades in whom we assessed the utility of a CHA2DS2-VASc score in the prediction of VSO. The CHA2DS2-VASc score was calculated retrospectively based on the clinical data. The whole study population was divided into two groups, based on the presence (group I) or absence (group II) of VSO. Using the receiver operating characteristic (ROC) curve, we identified the optimal cut-off point for the CHA2DS2-VASc score that allowed the prediction of the absence of VSO.

Results: The venography was performed in 223 consecutive patients aged on average 68.2years (25.7–95.3), 77 females (34.5%). The presence of VSO was detected in 79 (35.4%) patients aged 68.3 ± 14.1 years, 30 female (40%) patients—group I. The level of the cut-off point for the CHA2DS2-VASc score that allowed the prediction of the absence of VSO was 3.0.

Conclusion: In the whole population the incidence of VSO amounted to 35.4%. The result of the CHA2DS2-VASc score was a destimulant of VSO occurrence and was characterized by moderate sensitivity (73.4%) and specificity (42.4%) in predicting the absence of VSO. The most significant factor, which prevented VSO development was diabetes.
Original languageEnglish
Pages (from-to)P164-169
JournalInternational Journal of Cardiology
Early online date14 May 2016
Publication statusPublished - 1 Sep 2016

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