Projects per year
Abstract
The X-ray crystal structure of Shewanella oneidensis OmcA, an extracellular decaheme cytochrome involved in mineral reduction, was solved to a resolution of 2.7 Å. The four OmcA molecules in the asymmetric unit are arranged so the minimum distance between heme 5 on adjacent OmcA monomers is 9 Å, indicative of a transient OmcA dimer capable of intermolecular electron transfer. A previously identified hematite binding motif was identified near heme 10, forming a hydroxylated surface that would bring a heme 10 electron egress site to ∼ 10 Å of a mineral surface.
Original language | English |
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Pages (from-to) | 1886-1890 |
Journal | FEBS Letters |
Volume | 588 |
Issue number | 10 |
DOIs | |
Publication status | Published - 21 May 2014 |
Keywords
- Multiheme cytochrome
- Mineral respiration
- Electron transfer
- Shewanella
- c-Type heme
- Outer membrane
- Metalloprotein
Profiles
-
Julea Butt
- School of Biological Sciences - Professor of Biophysical Chemistry
- Centre for Molecular and Structural Biochemistry - Member
- Centre for Photonics and Quantum Science - Member
- Chemistry of Life Processes - Member
- Chemistry of Light and Energy - Member
- Energy Materials Laboratory - Member
- Molecular Microbiology - Member
Person: Research Group Member, Research Centre Member, Academic, Teaching & Research
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Tom Clarke
- School of Biological Sciences - Professor
- Centre for Molecular and Structural Biochemistry - Member
- Energy Materials Laboratory - Member
- Molecular Microbiology - Member
Person: Research Group Member, Research Centre Member, Academic, Teaching & Research
-
Andrew Gates
- School of Biological Sciences - Associate Professor in Bacterial Bioenergetics
- Centre for Molecular and Structural Biochemistry - Member
- Molecular Microbiology - Member
Person: Research Group Member, Research Centre Member, Academic, Teaching & Research
Projects
- 2 Finished
-
Molecular Basis for Controlled Transmembrane Electron Transfer
Clarke, T., Butt, J. & Richardson, D.
Biotechnology and Biological Sciences Research Council
1/01/13 → 31/12/15
Project: Research