Thiol redox and pKa properties of mycothiol, the predomiant low molecular weight thiol cofactor in the Actinomycetes

Sunil V Sharma, Koen Van Laer, Joris Messens, Chris James Hamilton (Lead Author)

Research output: Contribution to journalLetterpeer-review

22 Citations (Scopus)
17 Downloads (Pure)


Herein, the thiol pKa and standard redox potential of mycothiol, the major low molecular weight thiol cofactor in the actinomycetes, are reported. The measured standard redox potential reveals substantial discrepancies in one or more of the other previously measured intracellular parameters that are relevant to mycothiol redox biochemistry.
Original languageEnglish
Pages (from-to)1689–1692
Issue number18
Early online date22 Jun 2016
Publication statusPublished - 15 Sep 2016


  • Mycothiol
  • redox potential
  • thiol pKa

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