Thrombosis of a prosthetic mitral valve after withdrawal of phenprocoumon therapy

Dietmar Steverding, Andreas Wilke, Christian M. Wende, Michael Horst

Research output: Contribution to journalArticlepeer-review


Patients with prosthetic heart valves require lifelong oral anticoagulant therapy based on vitamin K antagonists. These patients may need interruption of their anticoagulant therapy if they have to undergo surgery. The clinical challenge is to identify patients who can safely undergo surgery while continuing their vitamin K antagonist treatment and those who have to take short-acting heparin as part of a bridging therapy. Here we present a case of a patient with a prosthetic mitral valve whose oral anticoagulant therapy was unnecessarily discontinued by the GP prior to an upcoming cataract surgery. As a result, the patient developed thrombosis of the prosthetic mitral valve which needed to be surgically replaced.
Original languageEnglish
Pages (from-to)298-300
Number of pages3
JournalCardiology Research
Issue number6
Publication statusPublished - 2011

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