Trade-off between growth and immunity: role of brassinosteroids

Rosa Lozano-Durán, Cyril Zipfel

Research output: Contribution to journalArticlepeer-review

183 Citations (Scopus)


A balance between growth and immunity exists in plants. Recently, the growth-promoting hormones brassinosteroids (BR) have emerged as crucial regulators of the growth-immunity trade-off, although the molecular mechanisms underlying this role remained unclear. New evidence obtained from the model plant Arabidopsis thaliana points at an indirect crosstalk between BR signaling and immunity, mediated by the transcription factors BZR1 and HBI1, which suppress immunity upon BR perception. The core transcriptional cascade formed by BZR1 and HBI1 seems to act as a regulatory hub on which multiple signaling inputs impinge, ensuring effective fine-tuning of the trade-off between growth and immunity in a timely and cost-efficient manner.

Original languageEnglish
Pages (from-to)12-19
Number of pages8
JournalTrends in Plant Science
Issue number1
Early online date30 Sep 2014
Publication statusPublished - Jan 2015


  • Arabidopsis
  • Arabidopsis Proteins
  • Brassinosteroids
  • Signal Transduction
  • Transcription Factors

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