Translocations in solid tumours

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)


Specific chromosomal translocations have now been identified in a variety of solid tumour types. Recent developments in this field include the identification of novel genes involved in the t(X;18) synovial sarcoma translocation and the discovery that the high-mobility group protein gene, HMGI-C, is involved in the chromosome 12 rearrangements found in lipomas and uterine leiomyomas. These discoveries may have important implications for the strategies used in tumour diagnosis and treatment.

Original languageEnglish
Pages (from-to)71-75
Number of pages5
JournalCurrent Opinion in Genetics and Development
Issue number1
Publication statusPublished - Feb 1996

Cite this