Abstract
Specific chromosomal translocations have now been identified in a variety of solid tumour types. Recent developments in this field include the identification of novel genes involved in the t(X;18) synovial sarcoma translocation and the discovery that the high-mobility group protein gene, HMGI-C, is involved in the chromosome 12 rearrangements found in lipomas and uterine leiomyomas. These discoveries may have important implications for the strategies used in tumour diagnosis and treatment.
Original language | English |
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Pages (from-to) | 71-75 |
Number of pages | 5 |
Journal | Current Opinion in Genetics and Development |
Volume | 6 |
Issue number | 1 |
DOIs | |
Publication status | Published - Feb 1996 |