Trial of the route of early nutritional support in critically ill adults

Sheila E Harvey, Francesca Parrott, David A Harrison, Danielle E Bear, Ella Segaran, Richard Beale, Geoff Bellingan, Richard Leonard, Michael G Mythen, Kathryn M Rowan, CALORIES Trial Investigators

Research output: Contribution to journalArticlepeer-review

416 Citations (Scopus)


Uncertainty exists about the most effective route for delivery of early nutritional support in critically ill adults. We hypothesized that delivery through the parenteral route is superior to that through the enteral route.
Original languageEnglish
Article number25271389
Pages (from-to)1673-1684
Number of pages12
JournalNew England Journal of Medicine
Issue number18
Publication statusPublished - 30 Oct 2014


  • Adult
  • Aged
  • Critical Illness
  • Energy Intake
  • Enteral Nutrition
  • Female
  • Humans
  • Hypoglycemia
  • Intensive Care Units
  • Male
  • Middle Aged
  • Parenteral Nutrition
  • Vomiting

Cite this